Anti-allergic Activity of Naringenin Chalcone from a Tomato Skin Extract
スポンサーリンク
概要
- 論文の詳細を見る
The anti-allergic activity of a tomato extract was studied by using an in vitro histamine-release assay. The tomato skin extract exerted the strongest inhibition of histamine release. Chlorogenic acid, rutin and naringenin were identified in the 60% ethanol extract of tomato skin. However, the extract contained an unknown compound which strongly inhibited histamine release. This active compound in tomato skin was identified as naringenin chalcone (trans-2′4′6′4-tetrahydroxychalcone). Naringenin chalcone inhibited histamine release with an IC50 value of 68 μg/ml. The anti-allergic activity of the tomato skin extract was next investigated by the in vivo mouse ear-swelling response. We found that naringenin chalcone showed the strongest inhibitory effect of the polyphenols of the tomato skin extract. These results indicate that a tomato skin extract could inhibit allergic reactions.
- 社団法人 日本農芸化学会の論文
- 2004-08-23
著者
-
YAMAMOTO Taichi
Research and Development Division, Kikkoman Corporation
-
OBATA Akio
Research and Development Division, Kikkoman Corporation
-
SAITO Makoto
Research and Development Division, Kikkoman Corporation
-
KIKUCHI Mamoru
Research and Development Division, Kikkoman Corporation
-
YOSHIMURA Mineka
Research and Development Division, Kikkoman Corporation
-
Saito Makoto
Research And Development Division Kikkoman Corporation
-
Yoshimura Mineka
Research & Development Division Kikkoman Corporation
-
Saito M
Department Of Biotechnology And Life Science Tokyo University Of Agriculture And Technology
-
TSUJI Ryohei
Research and Development Division, Kikkoman Corporation
-
Kikuchi Masanori
Department Of Food Production And Utility Development Graduate School Of Dairy Science Research Raku
-
YAMAGUCHI Fumio
Research & Development Division, Kikkoman Corporation
-
KOUCHI Tomoko
Research & Development Division, Kikkoman Corporation
-
Yamaguchi Fumio
Research & Development Division Kikkoman Corporation
-
Obata A
Kikkoman Corp. Chiba Jpn
-
Obata Akio
Research & Development Division Kikkoman Corporation
-
Tsuji Ryouhei
Res. And Dev. Div. Kikkoman Corp.
-
Tsuji Ryohei
Research And Development Division Kikkoman Corporation
-
Kouchi Tomoko
Research & Development Division Kikkoman Corporation
-
Kikuchi M
Kikkoman Corp. Chiba Jpn
-
Kikuchi Mamoru
Res. And Dev. Div. Kikkoman Corp.
-
Kikuchi Mamoru
Research & Development Division Kikkoman Corporation
-
Kikuchi M
Res. And Dev. Div. Kikkoman Corp.
-
Saito M
Research And Development Division Kikkoman Corporation
-
Yamamoto Taichi
Department Of Applied Molecular Biosciences Graduate School Of Bioagricultural Sciences Nagoya Unive
-
Yamamoto Taichi
Research & Development Division Kikkoman Corporation
-
Yoshimura Mineka
キッコーマン研究本部
-
Saito Makoto
Research & Development Division Kikkoman Corporation
関連論文
- Effects of Oral Administration of Ellagic Acid-Rich Pomegranate Extract on Ultraviolet-Induced Pigmentation in the Human Skin
- A Comprehensive Gene Expression Analysis Toward the Understanding of Growth and Differentiation of Tobacco BY-2 Cells
- Cytotoxicity of Extracts from Alternaria alternata against Cultured Tobacco BY-2 Cells
- Distinctive Effects of Menadione on the In Vivo Catalase Activity and the Adaptation to Hydrogen Peroxide Stress in Yeast Cells
- PURIFICATION OF CHITINASE FROM TOBACCO CULTURED CELL BY-2
- QUANTITATIVE APPLICATION OF ELECTRIC STIMULUS BY THE SINGLE-CELL METHOD
- Intracellular Fate of 2-NBDG, a Fluorescent Probe for Glucose Uptake Activity, in Escherichia coli Cells
- Cell-lytic Activity of Tobacco BY-2 Induced by a Fungal Elicitor from Alternaria alternata Attributed to the Expression of a Class I β-1, 3-Glucanase Gene
- Isolation of a Novel Isozyme of Tobacco BY-2 Chitinase Induced by a Fungal Elicitor
- Effects of High Pressure Treatment on the Ultrastructure and Solubilization of Isolated Myofibrils(Food & Nutrition)
- Oral Intake of Soy Isoflavone Aglycone Improves the Aged Skin of Adult Women
- Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats
- Safety Evaluation of Flavonoids-Containing Tomato Skin Extract
- Minimum-Energy State of an Axisymmetric Toroidal Plasma
- Application of an Aspergillus saitoi Protease Preparation to Soybean Curd to Modify Its Functional and Rheological Properties
- Transforming growth factor-alpha (TGF α)-producing gastric carcinoma with acanthosis nigricans: An endocrine effect of TGF αin the pathogenesis of cutaneous paraneoplastic syndrome and epithelial hyperplasia of the esophagus.
- タバコ培養細胞細胞間膜への定量的傷害印加のための微小電極システムの応用
- Genotoxicity Studies of Fermented Soybean Extract
- Synthesis of 4-Hydroxy-3(2H)-furanone Acyl Derivatives and Their Anti-cataract Effect on Spontaneous Cataract Rats (ICR/f)
- Antioxidative Activities of 4-Hydroxy-3 (2H)-furanones and Their Anti-cataract Effect on Spontaneous Cataract Rat (ICR/f)
- Triterpene Alcohols in the Seed Oils of Momordica charantia L.
- Simultaneous Imaging of Multiple Fluorescent Probes in Bio-Cells
- Cloning anc Sequencing of the Alkaline Protease cDNA from Aspergillus oryzae(Microbilolgy & Fermentation Industry)
- An Evaluation of the Clinical Efficacy of Tomato Extract for Perennial Allergic Rhinitis
- 電気的シグナルによるイネ単一細胞内へのCa〔2+〕流入の制御
- CONTROL OF CALCIUM INFLUX INTO A SINGLE RICE CELL WITH AN ELECTRIC SIGNAL
- Automatic Mapping of Viable Microbial Cells Distributed in the Surface Layer of Cotton Fabrics
- Anti-allergic Activity of Naringenin Chalcone from a Tomato Skin Extract
- Viable Cell Detection by the Combined Use of Fluorescent Glucose and Fluorescent Glycine(Food & Nutrition Sience)
- ISOLATION AND ANALYSIS OF TOBACCO CULTURED CELL BY-2 CHITINASE (TBC)
- Total Syntheses of All Four Stereoisomers of Piscidic Acid via Catalytic Asymmetric Dihydroxylation of (Z)- and (E)-trisubstituted Olefins
- Total Synthesis of (+)-(2S, 3R)-Piscidic Acid via Catalytic Asymmetric Dihydroxylation of a Trisubstituted Olefin
- タバコ培養細胞における膜電位制御と膜インピーダンスの同時計測
- Effects of High Pressure Treatment on Ca^ Release and Ca^ Uptake of Sarcoplasmic Reticulum
- Pressure-induced Ca^ Release from Rabbit Sarcoplasmic Reticulum
- Effect of High Pressure Treatment on the Ultrastructure and Myofibrillar Protein of Beef Skeletal Muscle(Food & Nutrition)
- Functional Analysis of a Rice Putative Voltage-Dependent Ca^ Channel, OsTPC1, Expressed in Yeast Cells Lacking its Homologous Gene CCH1
- Lowering Effect of an Isoflavone-Rich Fermented Soybean Extract on the Serum Cholesterol Concentrations in Female Rats, with or without Ovariectomy, but Not in Male Rats
- Lack of an Inducible Effect of Dietary Soy Isoflavones on the mRNA Abundance of Hepatic Cytochrome P-450 Isozymes in Rats
- Two Novel Oligosaccharides Formed by 1^F-Fructosyltransferase Purified from Roots of Asparagus (Asparagus officinalis L.)(Food & Nutrition Science)
- Clinical Efficacy of Halophilic Lactic Acid Bacterium Tetragenococcus halophilus Th221 from Soy Sauce Moromi for Perennial Allergic Rhinitis
- Efficient Production of γ-Polyglutamic Acid by Bacillus subtilis (natto) in Jar Fermenters
- Detection ofγ-Polyglutamic Acid (γ-PGA) by SDS-PAGE
- An Efficient Preparation of Acetyl Isoflavone Glucoside
- Single-Cell Imaging of the Ca^2+ Influx into Bovine Endothelial Cells Occurring in Response to an Alternating Electric
- Analysis of the HRR Stress Field at the Three-Dimensional Crack TIP : Analysis of CT and CCT Specimens
- Comprehensive Analysis of Glucan Elicitor-Regulated Gene Expression in Tobacco BY-2 Cells Reveals a Novel MYB Transcription Factor Involved in the Regulation of Phenylpropanoid Metabolism
- Primary tubular adenocarcinoma arising in the duodenal limb of reconstructed gastroduodenostomy for signet-ring cell carcinoma of the stomach
- Thermal changes in synthetic deuterioxyapatite
- Beneficial Effects of Grape Seed Extract on Malondialdehyde-Modified LDL
- Inhibitory Effect of an Ellagic Acid-Rich Pomegranate Extract on Tyrosinase Activity and Ultraviolet-Induced Pigmentation
- Isolation and Characterization of a Novel Immunomodulating Fraction from Soybeans
- Substrate Specificity and Subsite Affinities of β-Fructofuranosidase from Bifidobacterium adolescentis G1
- Purification and Some Properties of β-Fructofuranosidase from Bifidobacterium adolescentis G1
- The Production of β-Fructofuranosidase from Bifidobacterium spp.
- Study on the Ductile Fracture of a Surface Crack : (Growth of a Surface Crack and Finite Element Analysis)
- Procyanidin B1 Is Detected in Human Serum after Intake of Proanthocyanidin-rich Grape Seed Extract(Food & Nutrition Science)
- ANALYSIS OF RICE CHITINASE GENE EXPRESSION USING GFP REPORTER GENE
- ELECTRIC CONTROL OF INTERCELLULAR TRANSLOCATION OF A FLUOROCHOME IN PLANT CELLS.
- Decrease in the Gel Strength of Tofu Caused by an Enzyme Reaction during Soybean Grinding and Its Control
- Degradation of Sulfhydryl Groups in Soymilk by Lipoxygenases during Soybean Grinding
- Identification of the Transactivating Region of the Homeodomain Protein, Hex
- Purification and Identification of an Angiotensin I-converting Enzyme Inhibitor from Soy Sauce
- Purification and Some Properties of Sucrose Phosphorylase from Leuconostoc mesenteroides(Biological Chemistry)
- Preparation and Characterization of Anti-Fumonisin Monoclonal Antibodies
- Some Culture Conditions for the Production of Cyclodextrin-hydrolyzing Enzyme from Bacillus sphaericus(Microbiology & Fermentation Industry)
- CHITINASE GENE EXPRESSION BY VARIOUS STIMULI AND ANALYSIS OF INTERCELLULAR SIGNAL TRANSLOCATION IN RICE LEAF
- THE ESTABLISHMENT OF A NEW BIOLOGICAL ASSAY SYSTEM FOR SIMULTANEOUS MEASUREMENT OF BONE RESORPTION AND BONE MINERALIZATION IN ORGAN CULTURES OF CHICK EMBRYONIC FEMUR
- Antihypertensive and Natriuretic Effects of Less-Sodium Soy Sauce Containing γ-Aminobutyric Acid in Spontaneously Hypertensive Rats
- Analysis of Ground Effects on Aerodynamic Characteristics of Aerofoils Using Boundary Layer Approximation
- Application of an Aspergillus saitoi Protease Preparation to Soybean Curd to Modify Its Functional and Rheological Properties
- Evidence for the plasma membrane localization of a putative voltage-dependent Ca^ channel, OsTPC1, in rice
- Identification and Characterization of the Hematopoietic Cell-Specific Enhancer-Like Element of the Mouse Hex Gene
- Carotenoid Components in Soybean Seeds Varying with Seed Color and Maturation Stage
- Emulsifying and Oil-binding Properties of Bovine Serum Albumin and Its Enzymatic Hydrolyzate
- Adenocarcinoma of the Ileum Producing Carbohydrate Antigen 19-9 : Report of a Case
- J INTEGRAL EVALUATION OF A CRACK IN THE PRESSURE VESSEL UNDER THERMAL TRANSIENT LOADING
- Study on Thickness Effect of Three-Point-Bend Specimen
- Mixed-Mode Fracture Test of CFRP Laminates
- Electroless Copper Deposition Using Fe(II) Complex as a Reducing Agent
- Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
- Novel Histamine Measurement by HPLC Analysis Used to Assay Histidine Decarboxylase Inhibitory Activity of Shoyuflavones from Soy Sauce
- THREE DIMENSIONAL CRACK GROWTH ANALYSIS BY THE T. N. P. METHOD
- J and J^^ Integral Evaluation of a Crack in a Reactor Pressure Vessel under Pressurized Thermal Shock
- Ductile Fracture of Aluminum Alloys : Observation of the Fracture Process by FRASTA and FEM Simulation
- Paleoecological and Paleoenvironmental Changes in Lagoon Notoro-Ko (Japan) during the Last 200 Years Based on Diatom Assemblages and Sediment Chemistry(Earth Surface Processes, Natural Disasters and Historical Environmental Changes)
- Paleoecological and Paleoenvironmental Changes in Lagoon Notoro-Ko (Japan) during the Last 200 Years Based on Diatom Assemblages and Sediment Chemistry
- Metabolite profiling of soy sauce using gas chromatography with time-of-flight mass spectrometry and analysis of correlation with quantitative descriptive analysis(BREWING AND FOOD TECHNOLOGY)
- Anti-Influenza Virus Effects of Elderberry Juice and Its Fractions
- Cobalt-free Materials for Nickel-metal Hydride Battery: Self-discharge Suppression and Overdischarge-resistance Improvement
- Metabolite profiling of soy sauce using gas chromatography with time-of-flight mass spectrometry and analysis of correlation with quantitative descriptive analysis
- Application of s-Version Finite Element Method to Two-Dimensional Fracture Mechanics Problems
- Renal Pelvic Cancer Revealed by Renal Biopsy