Quantitative Analysis of the Marker Compounds in Salvia miltiorrihiza Root and Its Phytomedicinal Preparations
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概要
- 論文の詳細を見る
A HPLC method is described in order to separate and identify 4 phenolic compounds including lithospermic acid B, 3,4-dihydroxyphenyllactic acid (danshensu), rosmarinic acid, and protocatechuic aldehyde as well as 3 lipophilic ones (tanshinone I, tanshinone II_A and cryptotanshinone) from the roots of Salvia miltiorrihiza or the herbal product containing S. miltiorrihiza available in Chinese or Japanese market. The influence of extractive conditions, such as method, solvents and time, on the 4 phenolic marker components in S. miltiorrihiza is well discussed. In order to investigate the stability of lithospermic acid B, the preparation samples of an injection and a granule were analyzed after being stored at 4℃, 20℃ and 40℃ for up to six months.
- 2005-05-01
著者
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Kano Y
Hokkaido Coll. Pharmacy Otaru Jpn
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Kano Yoshihiro
Department Of Kampo Medicinal Science Hokkaido Pharmacutical University
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Kano Y
Department Of Traditional Medicinal Science Hokkaido College Of Pharmacy
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Kano Yoshihiro
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Yuan D
Department Of Traditional Chinese Medicine Shenyang Pharmaceutical University
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Yuan Dan
Department Of Traditional Medicinal Science Hokkaido College Of Pharmacy
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Yuan Dan
Department Of Traditional Chinese Medicinal Sciences Shenyang Pharmaceutical University
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MAKINO Toshiaki
Department of Kampo Medicinal Science, Hokkaido College of Pharmacy
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Katagiri Y
Hokkaido Institute Of Pharmaceutical Sciences
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Pan Ying
Department Of Traditional Chinese Medicine Shenyang Pharmaceutical University
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Yuan D
Shenyang Pharmaceutical Univ. Shenyang Chn
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Makino T
Department Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Kyoto University
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Fu Wen
Department Of Traditional Chinese Medicine Shenyang Pharmaceutical University
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Makino T
Dep. Of Pharmacognosy Graduate School Of Pharmaceutical Sci. Nagoya City Univ.
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Makino Toshiaki
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Kano Yoshihiro
Iskra Industry Co. Ltd.
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Makino Toshiaki
Department Of Chemistry Faculty Of Science Okayam University Of Science
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Makino Taketoshi
R&d Center Sunstar Inc.
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Makino Toshiaki
Dep. Of Pharmacognosy Graduate School Of Pharmaceutical Sciences Nagoya City Univ.
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Yuan Dan
Department Of Traditional Chinese Medicines Shenyang Pharmaceutical University
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Kano Yoshihiro
Department Of Gastroenterological Surgery Osaka University Graduate School Of Medicine
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Pan Ying-ni
Department of Traditional Chinese Medicine, Shenyang Pharmaceutical University
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Fu Wen-wei
Department of Traditional Chinese Medicine, Shenyang Pharmaceutical University
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