Analysis and Bioactive Evaluation of the Compounds Absorbed into Blood after Oral Administration of the Extracts of Vaccinium vitis-idaea in Rat(Pharmacognosy)
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概要
- 論文の詳細を見る
In order to screen the active constituents of Vaccinium vitis-idaea L., the compounds absorbed into the rat blood after oral administration of ethanol extract of the stems and leaves of V. vitis-idaea (EEV) have been analyzed. Two compounds were detected in the plasma and identified as arbutin and fraxin, which are originally existed in the crude drug. Furthermore, the pharmacological effects of the two compounds involving EEV for curing acute and chronic respiratory tract infection were tested. The results showed that both arbutin and fraxin have the anti-inflammatory, anti-coughing and phlegm-removing effects. Therefore, it was ascertained that the arbutin and fraxin would be the main active constituents of V. vitis-idaea L.
- 公益社団法人日本薬学会の論文
- 2005-06-01
著者
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Kano Y
Hokkaido Coll. Pharmacy Otaru Jpn
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Kano Yoshihiro
Department Of Kampo Medicinal Science Hokkaido Pharmacutical University
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Kano Y
Department Of Traditional Medicinal Science Hokkaido College Of Pharmacy
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Kano Yoshihiro
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Katagiri Y
Hokkaido Institute Of Pharmaceutical Sciences
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Sun Hui
School Of Pharmacy Shenyang Pharmaceutical Univ.
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SUN Hui
Heilongjiang University of Traditional Chinese Medicine
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Makino Toshiaki
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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WANG Xijun
Heilongjiang University of Traditional Chinese Medicine
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Kano Yoshihiro
Iskra Industry Co. Ltd.
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FAN Yuling
Heilongjiang University of Traditional Chinese Medicine
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LI Lijing
Heilongjiang University of Traditional Chinese Medicine
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Makino Toshiaki
Department Of Chemistry Faculty Of Science Okayam University Of Science
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Wang Xijun
Coll. Of Pharmacy Heilongjiang Univ. Of Chinese Medicine
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Kano Yoshihiro
Department Of Gastroenterological Surgery Osaka University Graduate School Of Medicine
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