Pharmacological Properties of Galenical Preparation-13-Metabolites in Rat Urine of Orally Administered Evodia Fruits(呉茱萸)Extract
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概要
- 論文の詳細を見る
After the oral administration of a methanol extract of "Evodia Fruit (呉茱萸)," rat urine was examined for its metabolites by using HPLC equipped with a fluorescence detector. The 4-quinolone type compound 5-(1, 4-dihydro-1-methyl-4-oxo-2-quinolin-2-yl)-pentanoic acid was detected as the main metabolite in the urine, and it was seemed to be derived from evocarpine which was contained in the crude drug, Evodia Fruit.
- 日本生薬学会の論文
- 1989-09-20
著者
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Kano Y
Department Of Traditional Medicinal Science Hokkaido College Of Pharmacy
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KOMATSU Ken-ichi
Department of Kampo Medicinal Science, Hokkaido College of Pharmacy
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Komatsu Ken-ichi
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Komatsu Ken-ichi
Hokkaido College Of Pharmacy
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Kano Yoshihiro
Hokkaido Institute Of Pharmaceutical Science
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Yasuda Masaho
Hokkaido Institute Of Pharmaceutical Sciences
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Saito Ken-ichi
Hokkaido Institute Of Pharmaceutical Science
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KANEMAKI SATORU
Hokkaido Institute of Pharmaceutical Sciences
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