Regulation of Gelatin-Binding Protein 28 (GBP28) Gene Expression by C/EBP
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概要
- 論文の詳細を見る
We have previously reported the isolation of human gelatin-binding protein 28 (GBP28) gene which is specifically expressed in adipose tissue. The transcriptional activity of the flanking region of the GBP28 gene was examined by the transient transfection of promoter-luciferase reporter constructs into 3T3 adipocytes and electrophoretic mobility shift assay. This revealed the existence of a protein which binds to the 5'-flanking region of the GBP28 gene in nuclear extracts from human adipose tissue, but not in nuclear extracts from mouse liver. The C/EBP sites contained in this region are thought to take part in the regulation of GBP28 gene expression.
- 社団法人日本薬学会の論文
- 1999-11-15
著者
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戸部 敞
昭和大学薬学部
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Choi-miura Nam-ho
Department Of Physiological Chemistry School Of Pharmaceutical Sciences Showa University
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Saito K
Department Of Kampo Medicinal Science Hokkaido College Of Pharmacy
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Saito Kiyomi
Department of phamacology, showa University School of Medicine
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Saito Kiyomi
Department Of Phamacogenomics School Of Phamaceutical Sciences Showa University
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TOBE Takashi
Department of Physiological Chemistry, School of Pharmaceutical Sciences Showa University
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TOMITA Motowo
Department of Physiological Chemistry, School of Pharmaceutical Sciences Showa University
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YODA Madoka
Department of Physiological Chemistry, School of Pharmaceutical Sciences, Showa University
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NAKANO Yasuko
Pharmaceutical and Medical Devices Evaluation Center, National Institute of Health Sciences
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Nakano Yoshinori
Pharmaceutical Development Laboratories Pharmaceutical Production Division Takeda Chemical Industrie
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Choi‐miura N‐h
Department Of Physiological Chemistry School Of Pharmaceutical Sciences Showa University
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斉藤 謙一
Department Of Physiology And Anatomy Nihon University College Of Pharmacy
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冨田 昌弘
Department Of Physiological Chemistry School Of Pharmaceutical Sciences Showa University
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Tomita Motowo
Department Of Hygienic Chemistry School Of Pharmaceutical Sciences Showa University
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Tobe Takashi
Department Of Biochemistry School Of Medicine Showa University
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Saito K
Department Of Physiology And Anatomy Nihon University College Of Pharmacy
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Nakano Yasuko
Dep. Of Pharmacogenomics School Of Pharmacy Showa Univ.
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Saguchi Ken-ichi
Laboratory Of Biopharmaceutics School Of Pharmaceutical Sciences Showa University
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Yoda Madoka
Department Of Physiological Chemistry School Of Pharmaceutical Sciences Showa University
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Shinozaki Kazuo
Riken Kanagawa Jpn
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Sasaki Kanako
Riken Kanagawa Jpn
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