国立がんセンター中央病院における5-HT_3受容体拮抗剤の使用実態調査

概要

論文の詳細を見る
At the National Cancer Center Hospital, serotonin (5-HT_3) receptor antagonists are used in chemotherapy regimens including anticancer agents with a strong emetic action to prevent nausea and vomiting. With a view to standardizing usage, we conducted a survey to determine how 5-HT_3 receptor antagonists were being used in our hospital. It was found that the type of 5-HT_3 receptor antagonist, diluent volume and infusion time varied among cancer therapy groups and among the 4 intraveneous 5-HT_3 receptor antagonists available in our hospital, granisetron was the most frequently used, though the administration method varied with the regimen. While the therapeutic goal of treatment with 5-HT_3 receptor antagonists is to completely eliminate nausea and vomiting due to anticancer agents, they should be used as efficiently as possible and for this purpose it is important to standardize the volume of the diluent and intravenous infusion time.
日本医療薬学会の論文
2007-05-10