ABSOLUTE STEREOSTRUCTURES OF ALISMALACTONE 23-ACETATE AND ALISMAKETONE-A 23-ACETATE, NEW SECO-PROTOSTANE AND PROTOSTANE-TYPE TRITERPENES WITH VASORELAXANT EFFECTS FROM CHINESE ALISMATIS RHIZOMA
スポンサーリンク
概要
- 論文の詳細を見る
New bioactive seco-protostane and protostane-type triterpenes, alismalactone 23-acetate and alismaketone-A 23-acetate, were isolated from Chinese Alismatis Rhizoma originating from Fukien province, the dried rhizoma of Alisma orientale JUZEP. Absolute stereostructures of the new triterpenes were determined on the basis of chemical and physicochemical evidence, which included chemical correlations with the known triterpene alisol B monoacetate. Alismalactone 23-acetate and alismaketone-A 23 acetate were found to show inhibitory activity on the contractions induced by a high concentration of K^+ in isolated aortic strips from rats.
- 公益社団法人日本薬学会の論文
- 1997-04-15
著者
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MATSUDA Hisashi
Kyoto Pharmaceutical University
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YOSHIKAWA Masayuki
Kyoto Pharmaceutical University
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山崎 幹夫
千葉大学薬学部
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MURAKAMI Toshiyuki
Kyoto Pharmaceutical University
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MURAKAMI Nobutoshi
Kyoto Pharmaceutical University
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YAMAHARA Johji
Kyoto Pharmaceutical University
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IKEBATA Akira
Kyoto Pharmaceutical University
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村上 啓寿
阪大院薬:presto
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Matsumura N
Res. Foundation Itsuu Lab. Tokyo Jpn
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Yamahara J
Kyoto Pharmaceutical University
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Ishikado Atsushi
Kyoto Pharmaceutical University
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Ikebata Akira
Kyoto Pharmaceutical University Misasagi
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YAMAHARA JOHJI
Kyoto College of Pharmacy
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MATSUDA HISASHI
Kyoto College of Pharmacy
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Murakami Toshiyuki
Kyoto Institute of Technology
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