Isolation and Structure Determination of cerebrosides from Garlic, the Bulbs of Allium sativum L.

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概要

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• Five cerebrosides, AS-1-1 (1), AS-1-2 (2), AS-1-3 (3), AS-1-4 (4), and AS-1-5 (5) were obtained from the CHCl_3-MeOH extract of Garlic, the bulbs of Allium sativum L. (Liliaceae). On the basis of spectroscopic results, structures of 1-5 have been elucidated. Compounds 1,2,and 5 were new cerebrosides. Compounds 3 and 4 were identified with the known glucocerebroside soya-cerebroside I and II, respectively, which have been previously obtained from soybean with ionophoretic activity. Positive ion FAB-MS/MS of the (M+Na)^+ ion gave important information on the length of the fatty acyl chain of the ceramide moiety.

• 公益社団法人日本薬学会の論文
• 1998-07-15

著者

• INAGAKI MASANORI

  Faculty of Pharmaceutical Sciences, Kyushu University

• HIGUCHI RYUICHI

  Faculty of Pharmaceutical Sciences, Kyushu University

• Isobe R

  Department Of Medical Electronics Engineering Faculty Of Engineering Towa University

• Isobe Ryuichi

  Tohwa University

• YAMADA Koji

  Faculty of Engineering, Saitama University

• Higuchi Ryuichi

  Graduate School Of Pharmaceutical Sciences Kyushu Univ.

• Higuchi Ryuichi

  Faculty Of Pharmaceutical Sciences Kyushu University

• Yamada K

  Graduate School Of Pharmaceutical Sciences Kyushu University

• ISOBE Ryuichi

  Department of Medical Electronics Engineering, Faculty of Engineering, Towa University

• HARADA Yasuo

  Faculty of Pharmaceutical Sciences, Kyushu University

• Itakura Y

  Institute For Otc Research Wakunaga Pharmaceutical Co. Ltd.

• Itakura Yoichi

  Institute For Otc Research Wakunaga Pharmaceutical Co. Ltd.

• Yamada Katsuya

  Graduate School Of Pharmaceutical Sciences Nagoya City University

• Isobe Ryuichi

  Department Of Medical Electronics Engineering Faculty Of Engineering Towa University

• Isobe R

  Faculty Of Pharmaceutical Sciences Kyushu University

• MATSUURA Hiromichi

  Institute for OTC Research, Wakunaga Pharmaceutical Co., Ltd.,

• Harada Y

  Administrator Of Hiroshima City Hospital Affairs Hiroshima

• Inagaki Masanori

  Faculty Of Pharmaceutical Sciences Kyushu University

• Ito Masaki

  The First Department Of Internal Medicine Mie University School Of Medicine

• Matsuura Hiromichi

  Institute For Otc Research Wakunaga Pharmaceutical Co. Ltd.

• Harada Yasuo

  Faculty Of Agriculture Kyushu University

• Yamada Koji

  Faculty Of Engineering Saitama University

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