Isolation and Structure of a Galactocerebroside from the Sea Cucumber Bohadschia argus

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概要

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• A galactocerebroside (BAC-4-4a) was obtained from its parent galactocerebroside molecular species (BAC-4) by using two types of reversed-phase HPLC column. The parent cerebroside BAC-4 has been isolated from less polar lipid fraction of CHCl_3/MeOH extract of sea cucumber Bohadschia argus, together with known typical types of glucocerebroside molecular species. The structure of BAC-4-4a was determined on the basis of chemical and spectroscopic evidences as 1-O-(β-D-galactopyranosyl)-(2S,3R,4E)-2[(2'R,15'Z)-2-hydroxytetracosenoylamino]-4-heptadecene-1,3-diol. This is the first report of isolation and structure determination of galactocerebroside from sea cucumber.

• 公益社団法人日本薬学会の論文
• 2009-03-01

著者

• INAGAKI MASANORI

  Faculty of Pharmaceutical Sciences, Kyushu University

• HIGUCHI RYUICHI

  Faculty of Pharmaceutical Sciences, Kyushu University

• MIYAMOTO Tomofumi

  Graduate School of Pharmaceutical Sciences, Kyushu University

• HIGUCHI Ryuichi

  Graduate School of Pharmaceutical Sciences, Kyushu University

• Miyamoto Tomofumi

  Graduate School Of Pharmaceutical Sciences Kyushu Univ.

• INAGAKI Masanori

  Graduate School of Pharmaceutical Sciences, Kyushu University

• Ikeda Yuriko

  Graduate School Of Pharmaceutical Sciences Kyushu University:faculty Of Pharmaceutical Sciences Naga

• Higuchi Ryuichi

  Graduate School Of Pharmaceutical Sciences Kyushu Univ.

• Yamada K

  Graduate School Of Pharmaceutical Sciences Kyushu University

• YAMADA Koji

  Graduate School of Pharmaceutical Sciences, Kyushu University

• ZHANG Xiao

  Graduate School of Pharmaceutical Sciences, Kyushu University

• ZHANG Bo

  Graduate School of Pharmaceutical Sciences, Kyushu University

• Zhang Bo

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Miyamoto T

  Graduate School Of Pharmaceutical Sciences Kyushu Univ.

• Yamada Katsuya

  Graduate School Of Pharmaceutical Sciences Nagoya City University

• Inagaki Masanori

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Yamada Kenji

  Tokyo University Of Pharmacy And Life Sciences School Of Pharmacy

• Maruta Tomoki

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Ito Masaki

  The First Department Of Internal Medicine Mie University School Of Medicine

• Zhang Xiao

  Graduate School Of Pharmaceutical Sciences Kyushu University

• Inagaki M

  Graduate School Of Pharmaceutical Sciences Chiba University

• Yamada Koji

  Graduate School Of Biomedical Sciences Nagasaki University

• Zhang Bo

  Graduate School of Engineering, Shizuoka University

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