Isolation and Structure Determination of Six Glucocerebrosides from the Starfish Luidia maculata
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概要
- 論文の詳細を見る
Two new glucocerebrosides, luidiacerebroside A (2) and B (6), were isolated from the cerebroside molecular species obtained from the less polar fraction of the CHCl_3/MeOH extract of the starfish Luidia maculata using HPLC. Four known cerebrosides, CE-2b (1), astrocerebroside B (3), acanthacerebroside B (4), and CE-3-2 (5) have also been isolated and characterized. The structures of these cerebrosides were determined on the basis of chemical and spectroscopic evidence. Mass spectrometry of dimethyl disulfide derivatives was useful for the determination of the double-bond position in the long-chain base.
- 公益社団法人日本薬学会の論文
- 2002-08-01
著者
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INAGAKI MASANORI
Faculty of Pharmaceutical Sciences, Kyushu University
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HIGUCHI Ryuichi
Graduate School of Pharmaceutical Sciences, Kyushu University
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Nakamura Katsuya
Medicinal Chemistry Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Nakamura K
Department Of Pharmacology School Of Pharmacy And Pharmaceutical Sciences Mukogawa Women's Univ
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Nakamura Kazufumi
Faculty Of Pharmaceutical Sciences Kyushu University
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INAGAKI Masanori
Graduate School of Pharmaceutical Sciences, Kyushu University
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Higuchi Ryuichi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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Nakamura Katsuji
Tsukuba Research Laboratories Eisai Co. Ltd.
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Nakamura K
Department Of Physiology Ii Iwate Medical University School Of Medicine
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KAWATAKE Satoshi
Faculty of Pharmaceutical Sciences, Kyushu University
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KAWATAKE Satoshi
Graduate School of Pharmaceutical Sciences, Kyushu University
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NAKAMURA Kazufumi
Graduate School of Pharmaceutical Sciences, Kyushu University
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Inagaki Masanori
Graduate School Of Pharmaceutical Sciences Kyushu University
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Ito Masaki
The First Department Of Internal Medicine Mie University School Of Medicine
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Kawatake Satoshi
Faculty Of Pharmaceutical Sciences Kyushu University
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