Isolation and Structure of Hematoside-Type Ganglioside from the Starfish Linckia laevigata
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概要
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A hematoside-type ganglioside, LLG-1 (1), has been obtained from the polar lipid fraction of the chloroform/methanol extract of the starfish Linckia laevigata. The structure of the ganglioside has been determined on the basis of chemical and spectroscopic evidence as 1-O-[N-glycolyl-α-D-neuraminosyl-(2→3)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide. The ceramide moiety was composed of heterogeneous 2-hydroxy fatty acid and phytosphingosine units. This is the first report on the isolation and structure elucidation of naked hematoside-type ganglioside from echinoderms.
- 2009-02-01
著者
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INAGAKI MASANORI
Faculty of Pharmaceutical Sciences, Kyushu University
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HIGUCHI RYUICHI
Faculty of Pharmaceutical Sciences, Kyushu University
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HIGUCHI Ryuichi
Graduate School of Pharmaceutical Sciences, Kyushu University
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Miyamoto Tomofumi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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INAGAKI Masanori
Graduate School of Pharmaceutical Sciences, Kyushu University
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Higuchi Ryuichi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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Higuchi Ryuichi
Faculty Of Pharmaceutical Sciences Kyushu University
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MIYAMOTO Tomofumi
Faculty of Pharmaceutical Sciences, Kyushu University
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Miyamoto T
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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SAITO Takeshi
Faculty of Pharmaceutical Sciences, Kyushu University
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Inagaki Masanori
Faculty Of Pharmaceutical Sciences Kyushu University
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Maruta Tomoki
Graduate School Of Pharmaceutical Sciences Kyushu University
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Ito Masaki
The First Department Of Internal Medicine Mie University School Of Medicine
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Saito Takeshi
Faculty Of Pharmaceutical Sciences Kyushu University
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Inagaki M
Graduate School Of Pharmaceutical Sciences Chiba University
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