Constituents of Crinoidea.2. Isolation and Structure of the Novel Type Gangliosides from the Feather Star Comanthus japonica
スポンサーリンク
概要
- 論文の詳細を見る
Two novel type gangliosides CJP2 and CJP3 have been obtained from the feather star Comanthus japonica. On the basis of methylation linkage analysis combined with ammonolysis and other chemical and spectroscopic evidence, the chemical structures of CJP2 and CJP3 were determined to be α-9-O-Me-NeuGc-(2→3)-inositolphosphoceramide and α-9-O-Me-NeuGc-(2→11)-α-9-O-Me-NeuGc-(2→3)-inositolphosphoceramide, respectively. These gangliosides are unique in that they are inositolphosphoceramide derivatives possessing sialic acid;such gangliosides have not previously been identified. The presence of 9-O-methyl-N-glycolyl-neuraminosyl residues is also unique in naturally occurring gangliosides.
- 公益社団法人日本薬学会の論文
- 2001-06-01
著者
-
INAGAKI MASANORI
Faculty of Pharmaceutical Sciences, Kyushu University
-
HIGUCHI Ryuichi
Graduate School of Pharmaceutical Sciences, Kyushu University
-
INAGAKI Masanori
Graduate School of Pharmaceutical Sciences, Kyushu University
-
Higuchi Ryuichi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
-
ARAO Kazuyoshi
Faculty of Pharmaceutical Sciences, Kyushu University
-
ARAO Kazuyoshi
Graduate School of Pharmaceutical Sciences, Kyushu University
-
Arao Kazuyoshi
Faculty Of Pharmaceutical Sciences Kyushu University
-
Inagaki Masanori
Graduate School Of Pharmaceutical Sciences Kyushu University
-
Ito Masaki
The First Department Of Internal Medicine Mie University School Of Medicine
関連論文
- Glyceroglycolipids Preventing tert-Butylhydroperoxide-Induced Cell Death from Microbacterium sp.and Corynebacterium aquaticum Strains
- Flavonoids from Brazilian Propolis
- Influenza A Virus-Binding Activity of Glycoglycerolipids of Aquatic Bacteria
- cis-Hinokiresinol, a Norlignan from Anemarrhena asphodeloides, Inhibits Angiogenic Response in Vitro and in Vivo (Pharmacognosy)
- 1,3-Dimethylisoguaninium, an Antiangiogenic Purine Analog from the Sponge Amphimedon paraviridis
- Isolation and Structures of Two New Compounds from the Essential Oil of Brazilian Propolis
- Cycloanthranilylproline-Derived Constituents from a Myxomycete Fuligo candida
- Wrightiamines A and B, Two New Cytotoxic Pregnane Alkaloids from Wrightia javanica
- A New Secoiridoid Glucoside from Brucea amarissima
- Lindbladione and Related Naphthoquinone Pigments from a Myxomycete Lindbladia tubulina
- Isolation and Structure of a Galactocerebroside from the Sea Cucumber Bohadschia argus
- Isolation and Structure of a Monomethylated Ganglioside Possessing Neuritogenic Activity from the Ovary of the Sea Urchin Diadema setosum
- Biologically active gangliosides from echinoderms
- Determination of the Absolute Configuration of Sialic Acids in Gangliosides from the Sea Cucumber Cucumaria echinata
- Neuritogenic Activity of Gangliosides from Echinoderms and Their Structure : Activity Relationship
- Constituents of Holothuroidea, 18. Isolation and Structure of Biologically Active Disialo- and Trisialo-Gangliosides from the Sea Cucumber Cucumaria echinata
- Constituents of Holothuroidea, 17. Isolation and Structure of Biologically Active Monosialo-Gangliosides from the Sea Cucumber Cucumaria echinata
- Constituents of Holothuroidea, 16. : Determination of Absolute Configuration of the Branched Methyl Group in Ante-iso Type Side Chain Moiety on Long Chain Base of Glucocerebroside from the Sea Cucumber Holothuria leucospilota
- Constituents of Holothuroidea, 15 : Isolation of Ante-iso Type Regioisomer on Long Chain Base Moiety of Glucocerebroside from the Sea Cucumber Holothuria leucospilota
- Constituents of Holothuroidea, 14. Isolation and Structure of New Glucocerebroside Molecular Species from the Sea Cucumber Stichopus japonicus
- Constituents of Holothuroidea, 13. Structure of Neuritogenic Active Ganglioside Molecular Species from the Sea Cucumber Stichopus chloronotus
- Constituents of Holothuroidea, 12. Isolation and Structure of Glucocerebrosides from the Sea Cucumber Holothuria pervicax
- Fucosyl-GM1a, an Endoglycoceramidase-resistant Ganglioside of Porcine Brain
- Structure of β-1,3-Xylooligosaccharides Generated from Caulerpa racemosa var. laete-virens β-1,3-Xylan by the Action of β-1,3-Xylanase
- A Novel Phosphatidylcholine Which Contains Pentadecanoic Acid at sn-1 and Docosahexaenoic Acid at sn-2 in Schizochytrium sp. F26-b
- Identification of Sixteen New Galactocerebrosides from the Starfish Protoreaster nodosus
- Isolation and Structure of Hematoside-Type Ganglioside from the Starfish Linckia laevigata
- Constituents of Crinoidea. 5. Isolation and Structure of a New Glycosyl Inositolphosphoceramide-Type Ganglioside from the Feather Star Comanthina schlegeli
- Isolation and Structure of Four New Ceramides from the Starfish Luidia maculata
- P-536 Isolation and Structure of Phosphoglycosphingolipids from the Okinawan Feather Stars, Comanthina schlegeli and Comanthus bennetti
- Identification of Five Phytosterols from Aloe Vera Gel as Anti-diabetic Compounds(Pharmacognosy)
- Biologically Active Glycosides from Asteroidea, 42. Isolation and Structure of a New Biologically Active Ganglioside Molecular Species from the Starfish Asterina pectinifera
- Isolation and Structure of a Galactocerebroside Molecular Species from the Starfish Culcita novaeguineae
- Biologically Active Glycosides from Asteroidea, 43. : Isolation and Structure of a New Neuritogenic-Active Ganglioside Molecular Species from the Starfish Linckia laevigata
- Biologically Active Glycosides from Asteroidea, 41. : Isolation and Structure Determination of Glucocerebrosides from the Starfish Linckia laevigata
- Constituents of Crinoidea, 4. Isolation and Structure of Ceramides and Glucocerebrosides from the Feather Star Comanthus japonica
- Constituents of Crinoidea.3. Isolation and Structure of a Glycosyl Inositolphosphoceramide-Type Ganglioside with Neuritogenic Activity from the Feather Star Comanthus japonica
- Isolation and Structure of a GD_3-Type Ganglioside Molecular Species Possessing Neuritogenic Activity from the Starfish Luidia maculata
- Isolation and Structure of Monomethylated GM_3-Type Ganglioside Molecular Species from the Starfish Luidia maculata
- Analgesic Components of Saposhnikovia Root : Saposhnikovia divaricata
- Six New Constituents from an Ascomycete, Chaetomlum quadrangulatum, Found in a Screening Study Focused on Monoamine Oxidase Inhibitory Activity
- Relationships of Subunits of Type-1 Serine/ Threonine Protein Phosphatase to Morphology and Aggregation of B Cells
- Monoamine Oxidase Inhibitory Naphthoquinone and/or Naphthalene Dimers from Lemuni Hitam (Diospyros sp.), a Malaysian Herbal Medicine
- Synthetic Studies on the Natural Multidrug Resistance Modulator, Irciniasulfonic Acid B
- Neuritogenic Activity-Guided Isolation of a Free Base Form Manzamine A from a Marine Sponge, Acanthostrongylophora aff. ingens(Thiele, 1899)
- Isolation and Structure Determination of Six Glucocerebrosides from the Starfish Luidia maculata
- Constituents of Ophiuroidea. 1. Isolation and Structure of Three Ganglioside Molecular Species from the Brittle Star Ophiocoma scolopendrina
- Differentiation of Diastereomeric Tertiarybutoxycarbonylprolylproline Ethyl Esters by Collision-Induced Dissociation of Sodium Adduct Ions in Fast Atom Bombardment Mass Spectrometry
- Constituents of Crinoidea.2. Isolation and Structure of the Novel Type Gangliosides from the Feather Star Comanthus japonica
- Constituents of Holothuroidea.10.^Isolation and Structure of a Biologically Active Ganglioside Molecular Species from the Sea Cucumber Holothuria leucospilota
- Differences in the Formation and Fragmentation of Sodium Adduct Ions between Tertiarybutoxycarbonyl-Protected Prolyproline Diastereomers in Fast Atom Bombardment Mass Spectrometry
- Constituents of Crinoidea. 1. Isolaton and Structure of Inositolphosphocermide from the Feather Star Comanthus japonica
- Structural Elucidation of Glycosphingolipids by Collision-Induced Dissociation of Sodium Ion Complex
- Novel preparation of free flowing spherically granulated dibasic calcium phosphate anhydrous for tabletting.
- NOVEL PREPARATION OF FREE FLOWING SPHERICALLY GRANULATED DIBASIC CALCIUM PHOSPHATE ANHYDROUS FOR DIRECT TABLETTING
- Separation of Leucas aspera, a Medicinal Plant of Bangladesh, Guided by Prostaglandin Inhibitory and Antioxidant Activities
- Isolation and Structure Determination of cerebrosides from Garlic, the Bulbs of Allium sativum L.
- Five New Chromones Possessing Monoamine Oxidase Inhibitory Activity from an Ascomycete, Chaetomium quadrangulatum
- Characterization and Application of Carbohydrate-binding Modules of β-1,3-xylanase XYL4
- Six Immunosuppressive Features from an Ascomycete, Zopfiella longicaudata. Found in a Screening Study Monitored by Immunomodulatory Activity
- Immunomodulatory Constituents from an Ascomycete, Emericella aurantio-brunnea
- Vimentin-Ser82 as a memory phosphorylation site in astrocytes
- P-18 Search for Inhibitors of Prion Replication from Natural Resources
- Cloning and Expression of Gene Encoding a Novel Endogkycoceramidase of Rhodococcus sp.Strain C9
- Constituents of Holothuroidea.9. Isolation and Structure of a New Ganglioside Molecular Species from the Sea Cucumber Holothuria pervicax
- P-261 SYNTHETIC STUDY OF CHONDROSIAMIDE A, A CYCLIC DEPSIPEPTIDE FROM THE MARINE SPONGE CHONDROSIA CHUCALLA
- Structural Elucidation of the Ceramide Moiety of Starfish Gangliosides by Collision-Induced Dissociation of the Sodium Ion Complex
- Inhibitory Effect of Norditerpenes on LPS-Induced TNF-α Production from the Okinawan Soft Coral, Sinularia sp.
- A New Secoiridoid Glucoside from Brucea amarissima
- Isolation of Diphlorethohydroxycarmalol from a Brown Alga Ishige okamurae
- Cytotoxic Pregnanes from Leaves of Adenium obesum
- Analgesic Components of Glehnia Root (Glehnia littoralis)
- Flavonoids from Brazilian Propolis
- Four New Cembrane Diterpenes Isolated from an Okinawan Soft Coral Lobophytum crassum with Inhibitory Effects on Nitric Oxide Production