Constituents of Ophiuroidea. 1. Isolation and Structure of Three Ganglioside Molecular Species from the Brittle Star Ophiocoma scolopendrina
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概要
- 論文の詳細を見る
Three ganglioside molecular species, OSG-0(1), OSG-1(2), and OSG-2(3)have been obtained from the polar lipid fraction of the chloroform/methanol extract of the brittle star Ophiocoma scolopendrina. The structures of these gangliosides have been cetermined on the basis of chemical and spectroscopic evidence as 1-O-[(N-glycolyl-α-D-neuraminosyl)-(2→6)-β-D-glucopyranosyl]-ceramide(1), 1-O-[8-O-sulfo-(N-acetyl-α-D-neuraminosyl)-(2→6)-β-D-glucopyranosyl]-ceramide(2)and 1-O-[(N-glycolyl-α-D-neuraminosyl)-(2→8)-(N-acetyl- and N-glycolyl-α-D-neuraminosyl)-(2→6)-β-D-glucopyranosyl]-ceramide(3). The ceramide moieties were composed of heterogeneous unsubstituted fatty acid, 2-hydroxy fatty acid and phytosphingosine units. Compounds 2 and 3 represent new ganglioside molecular species.
- 公益社団法人日本薬学会の論文
- 2001-12-01
著者
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INAGAKI MASANORI
Faculty of Pharmaceutical Sciences, Kyushu University
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HIGUCHI RYUICHI
Faculty of Pharmaceutical Sciences, Kyushu University
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Isobe R
Department Of Medical Electronics Engineering Faculty Of Engineering Towa University
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Isobe Ryuichi
Tohwa University
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Higuchi Ryuichi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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Higuchi Ryuichi
Faculty Of Pharmaceutical Sciences Kyushu University
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ISOBE Ryuichi
Department of Medical Electronics Engineering, Faculty of Engineering, Towa University
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Isobe Ryuichi
Department Of Medical Electronics Engineering Faculty Of Engineering Towa University
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Isobe R
Faculty Of Pharmaceutical Sciences Kyushu University
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SHIBAI Motohiro
Faculty of Pharmaceutical Sciences, Kyushu University
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Inagaki Masanori
Faculty Of Pharmaceutical Sciences Kyushu University
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Ito Masaki
The First Department Of Internal Medicine Mie University School Of Medicine
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Sakai Maki
Fac. Of Pharmaceutical Sciences Kyushu Univ.
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