Isolation and Structure of Monomethylated GM_3-Type Ganglioside Molecular Species from the Starfish Luidia maculata
スポンサーリンク
概要
- 論文の詳細を見る
Two monomethylated GM_3-Type ganglioside molecular species, 1 and 2, have been obtained from the polar lipid fraction of the chloroform/methanol extract of the starfish Luidia maculata. The structures of these gangliosides have been determined on the basis of chemical and spectroscopic evidence as 1-O-[8-O-methyl-(N-acetyl-α-_D-neuraminosyl)-(2→3)-β-_D-galactopyranosyl-(1→4)-β-_D-glucopyranosyl]-ceramide (1) and 1-O-[8-O-methyl-(N-glycolyl-α-_D-neuraminosyl)-(2→3)-β-_D-galactopyranosyl-(1→4)-β-_D-glucopyranosyl]-ceramide (2). The ceramide moieties were composed of heterogeneous unsubstituted fatty acid, 2-hydroxy fatty acid, sphingosine and phytosphingosine units. Compound 1, designated as LMG-3, represents new ganglioside molecular species. Compound 2 was a known ganglioside molecular species.
- 2002-10-01
著者
-
INAGAKI MASANORI
Faculty of Pharmaceutical Sciences, Kyushu University
-
HIGUCHI RYUICHI
Faculty of Pharmaceutical Sciences, Kyushu University
-
Isobe R
Department Of Medical Electronics Engineering Faculty Of Engineering Towa University
-
Isobe Ryuichi
Tohwa University
-
Miyamoto Tomofumi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
-
Higuchi Ryuichi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
-
Higuchi Ryuichi
Faculty Of Pharmaceutical Sciences Kyushu University
-
MIYAMOTO Tomofumi
Faculty of Pharmaceutical Sciences, Kyushu University
-
ISOBE Ryuichi
Department of Medical Electronics Engineering, Faculty of Engineering, Towa University
-
Isobe Ryuichi
Department Of Medical Electronics Engineering Faculty Of Engineering Towa University
-
Isobe R
Faculty Of Pharmaceutical Sciences Kyushu University
-
KAWATAKE Satoshi
Faculty of Pharmaceutical Sciences, Kyushu University
-
Inagaki Masanori
Faculty Of Pharmaceutical Sciences Kyushu University
-
Maruta Tomoki
Graduate School Of Pharmaceutical Sciences Kyushu University
-
Ito Masaki
The First Department Of Internal Medicine Mie University School Of Medicine
-
Kawatake Satoshi
Faculty Of Pharmaceutical Sciences Kyushu University
関連論文
- Glyceroglycolipids Preventing tert-Butylhydroperoxide-Induced Cell Death from Microbacterium sp.and Corynebacterium aquaticum Strains
- Flavonoids from Brazilian Propolis
- Study on "Signal" Constituents for the Evaluation of Animal Crude Drugs. II. Organic Acids
- 高速液体クロマトグラフィーによるドリンク剤中の生薬成分の分析法.主要生薬成分の各分析法の検討
- Electrochemical Method for Estimating the Antioxidative Effects of Methanol Extracts of Crude Drugs
- Investigation of "Signal" Constituents for the Evaluation of Animal Crude Drugs. I. Free Amino Acids and Total Amino Acids
- Contents of Lecithin and Choline in Crude Drugs
- Oleanene-Type Triterpene Glycosides from Puerariae Radix. IV. Six New Saponins from Pueraria lobata
- Oleanene-Type Triterpene Glycosides from Puerariae Radix. III.Three New Saponins from Pueraria thomsonii
- Three New Triterpenoidal Saponins Acylated with Monoterpenic Acid from Albizziae Cortex
- A New Steroidal Saponin from Dioscorea cayenensis
- A New Phenanthrene Glycoside and Other Constituents from Dioscorea opposita
- Influenza A Virus-Binding Activity of Glycoglycerolipids of Aquatic Bacteria
- Imidazo- and Triazoloquinolones as Antibacterial Agents. Synthesis and Structure-Activity Relationships
- cis-Hinokiresinol, a Norlignan from Anemarrhena asphodeloides, Inhibits Angiogenic Response in Vitro and in Vivo (Pharmacognosy)
- 1,3-Dimethylisoguaninium, an Antiangiogenic Purine Analog from the Sponge Amphimedon paraviridis
- Isolation and Structures of Two New Compounds from the Essential Oil of Brazilian Propolis
- Cycloanthranilylproline-Derived Constituents from a Myxomycete Fuligo candida
- Wrightiamines A and B, Two New Cytotoxic Pregnane Alkaloids from Wrightia javanica
- A New Secoiridoid Glucoside from Brucea amarissima
- Lindbladione and Related Naphthoquinone Pigments from a Myxomycete Lindbladia tubulina
- Regioselective Displacement Reactions of 1-Cyclopropyl-5,6,7,8-tetrafluoro-4(1H)-oxoquinoline-3-carboxylic Acid with Amine Nucleophiles
- Isolation and Structure of a Galactocerebroside from the Sea Cucumber Bohadschia argus
- Isolation and Structure of a Monomethylated Ganglioside Possessing Neuritogenic Activity from the Ovary of the Sea Urchin Diadema setosum
- Biologically active gangliosides from echinoderms
- Determination of the Absolute Configuration of Sialic Acids in Gangliosides from the Sea Cucumber Cucumaria echinata
- Neuritogenic Activity of Gangliosides from Echinoderms and Their Structure : Activity Relationship
- Constituents of Holothuroidea, 18. Isolation and Structure of Biologically Active Disialo- and Trisialo-Gangliosides from the Sea Cucumber Cucumaria echinata
- Constituents of Holothuroidea, 17. Isolation and Structure of Biologically Active Monosialo-Gangliosides from the Sea Cucumber Cucumaria echinata
- Constituents of Holothuroidea, 16. : Determination of Absolute Configuration of the Branched Methyl Group in Ante-iso Type Side Chain Moiety on Long Chain Base of Glucocerebroside from the Sea Cucumber Holothuria leucospilota
- Constituents of Holothuroidea, 15 : Isolation of Ante-iso Type Regioisomer on Long Chain Base Moiety of Glucocerebroside from the Sea Cucumber Holothuria leucospilota
- Constituents of Holothuroidea, 14. Isolation and Structure of New Glucocerebroside Molecular Species from the Sea Cucumber Stichopus japonicus
- Constituents of Holothuroidea, 13. Structure of Neuritogenic Active Ganglioside Molecular Species from the Sea Cucumber Stichopus chloronotus
- Constituents of Holothuroidea, 12. Isolation and Structure of Glucocerebrosides from the Sea Cucumber Holothuria pervicax
- Identification of Sixteen New Galactocerebrosides from the Starfish Protoreaster nodosus
- Isolation and Structure of Hematoside-Type Ganglioside from the Starfish Linckia laevigata
- Constituents of Crinoidea. 5. Isolation and Structure of a New Glycosyl Inositolphosphoceramide-Type Ganglioside from the Feather Star Comanthina schlegeli
- Isolation and Structure of Four New Ceramides from the Starfish Luidia maculata
- P-536 Isolation and Structure of Phosphoglycosphingolipids from the Okinawan Feather Stars, Comanthina schlegeli and Comanthus bennetti
- Identification of Five Phytosterols from Aloe Vera Gel as Anti-diabetic Compounds(Pharmacognosy)
- Biologically Active Glycosides from Asteroidea, 42. Isolation and Structure of a New Biologically Active Ganglioside Molecular Species from the Starfish Asterina pectinifera
- Isolation and Structure of a Galactocerebroside Molecular Species from the Starfish Culcita novaeguineae
- Biologically Active Glycosides from Asteroidea, 43. : Isolation and Structure of a New Neuritogenic-Active Ganglioside Molecular Species from the Starfish Linckia laevigata
- Biologically Active Glycosides from Asteroidea, 41. : Isolation and Structure Determination of Glucocerebrosides from the Starfish Linckia laevigata
- Constituents of Crinoidea, 4. Isolation and Structure of Ceramides and Glucocerebrosides from the Feather Star Comanthus japonica
- Constituents of Crinoidea.3. Isolation and Structure of a Glycosyl Inositolphosphoceramide-Type Ganglioside with Neuritogenic Activity from the Feather Star Comanthus japonica
- Isolation and Structure of a GD_3-Type Ganglioside Molecular Species Possessing Neuritogenic Activity from the Starfish Luidia maculata
- Isolation and Structure of Monomethylated GM_3-Type Ganglioside Molecular Species from the Starfish Luidia maculata
- Analgesic Components of Saposhnikovia Root : Saposhnikovia divaricata
- Six New Constituents from an Ascomycete, Chaetomlum quadrangulatum, Found in a Screening Study Focused on Monoamine Oxidase Inhibitory Activity
- Relationships of Subunits of Type-1 Serine/ Threonine Protein Phosphatase to Morphology and Aggregation of B Cells
- Collision-Activated Dissociation Spectra for the Characterization of the Diels-Alder Adducts between C_ and Troponoids
- Highly Thermally-Stable Diels-Alder Adducts of [60]Fullerene with 2-Cycloalkenones and Their Acetals
- Monoamine Oxidase Inhibitory Naphthoquinone and/or Naphthalene Dimers from Lemuni Hitam (Diospyros sp.), a Malaysian Herbal Medicine
- Synthetic Studies on the Natural Multidrug Resistance Modulator, Irciniasulfonic Acid B
- Neuritogenic Activity-Guided Isolation of a Free Base Form Manzamine A from a Marine Sponge, Acanthostrongylophora aff. ingens(Thiele, 1899)
- Isolation and Structure Determination of Six Glucocerebrosides from the Starfish Luidia maculata
- Constituents of Ophiuroidea. 1. Isolation and Structure of Three Ganglioside Molecular Species from the Brittle Star Ophiocoma scolopendrina
- Differentiation of Diastereomeric Tertiarybutoxycarbonylprolylproline Ethyl Esters by Collision-Induced Dissociation of Sodium Adduct Ions in Fast Atom Bombardment Mass Spectrometry
- Constituents of Crinoidea.2. Isolation and Structure of the Novel Type Gangliosides from the Feather Star Comanthus japonica
- Constituents of Holothuroidea.10.^Isolation and Structure of a Biologically Active Ganglioside Molecular Species from the Sea Cucumber Holothuria leucospilota
- Differences in the Formation and Fragmentation of Sodium Adduct Ions between Tertiarybutoxycarbonyl-Protected Prolyproline Diastereomers in Fast Atom Bombardment Mass Spectrometry
- Constituents of Crinoidea. 1. Isolaton and Structure of Inositolphosphocermide from the Feather Star Comanthus japonica
- Structural Elucidation of Glycosphingolipids by Collision-Induced Dissociation of Sodium Ion Complex
- Novel preparation of free flowing spherically granulated dibasic calcium phosphate anhydrous for tabletting.
- NOVEL PREPARATION OF FREE FLOWING SPHERICALLY GRANULATED DIBASIC CALCIUM PHOSPHATE ANHYDROUS FOR DIRECT TABLETTING
- Steroidal Saponins from the Roots of Smilax aspera subsp. mauritanica
- Separation of Leucas aspera, a Medicinal Plant of Bangladesh, Guided by Prostaglandin Inhibitory and Antioxidant Activities
- Isolation and Structure Determination of cerebrosides from Garlic, the Bulbs of Allium sativum L.
- Five New Chromones Possessing Monoamine Oxidase Inhibitory Activity from an Ascomycete, Chaetomium quadrangulatum
- Six Immunosuppressive Features from an Ascomycete, Zopfiella longicaudata. Found in a Screening Study Monitored by Immunomodulatory Activity
- Immunomodulatory Constituents from an Ascomycete, Emericella aurantio-brunnea
- Vimentin-Ser82 as a memory phosphorylation site in astrocytes
- Fast Atom Bombardment Tandem Mass Spectrometry of Benzyloxycarbonyl-Protected Tetrapeptide Derivatives Containing Proline
- P-18 Search for Inhibitors of Prion Replication from Natural Resources
- Sulfated Lupane Triterpene Derivatives and a Flavone C-Glycoside from Gypsophila repens
- P-478 Sulfated lupane triterpene derivatives and a flavone C-glycoside from Gypsophila repens
- PA56 ISOLATION AND STRUCTURE OF THE THREE GANGLIOSIDES FROM THE STARFISH ACANTHASTER PLANCI
- Constituents of Holothuroidea.9. Isolation and Structure of a New Ganglioside Molecular Species from the Sea Cucumber Holothuria pervicax
- PA25 ISOLATION AND STRUCTURES OF NEWLY CHARACTERIZED OLIGOGLYCOSIDE SULFATES FROM ASTEROIDEA
- P-261 SYNTHETIC STUDY OF CHONDROSIAMIDE A, A CYCLIC DEPSIPEPTIDE FROM THE MARINE SPONGE CHONDROSIA CHUCALLA
- Two New Triterpene Saponins from Eryngium campestre
- Structural Elucidation of the Ceramide Moiety of Starfish Gangliosides by Collision-Induced Dissociation of the Sodium Ion Complex
- Inhibitory Effect of Norditerpenes on LPS-Induced TNF-α Production from the Okinawan Soft Coral, Sinularia sp.
- A New Secoiridoid Glucoside from Brucea amarissima
- Isolation of Diphlorethohydroxycarmalol from a Brown Alga Ishige okamurae
- Cytotoxic Pregnanes from Leaves of Adenium obesum
- Analgesic Components of Glehnia Root (Glehnia littoralis)
- 高速液体クロマトグラフィーによる動物生薬の構成成分の測定法
- Flavonoids from Brazilian Propolis
- Four New Cembrane Diterpenes Isolated from an Okinawan Soft Coral Lobophytum crassum with Inhibitory Effects on Nitric Oxide Production