Determination of the Absolute Configuration of Sialic Acids in Gangliosides from the Sea Cucumber Cucumaria echinata
スポンサーリンク
概要
- 論文の詳細を見る
Enantiomeric pairs of sialic acid, D- and L-NeuAc (N-acetylneuraminic acid), were converted to D- and L-arabinose, respectively, by chemical degradation. Using this method, the absolute configuration of the sialic acid residues, NeuAc and NeuGc (N-glycolylneuraminic acid), in the gangliosides from the sea cucumber Cucumaria echinata was determined to be the D-form. Although naturally occurring sialic acids have been believed to be the D-form on the basis of biosynthetic evidence, this is the first report of the determination of the absolute configuration of the sialic acid residues in gangliosides using chemical methods.
- 公益社団法人日本薬学会の論文
- 2007-07-01
著者
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INAGAKI MASANORI
Faculty of Pharmaceutical Sciences, Kyushu University
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HIGUCHI RYUICHI
Faculty of Pharmaceutical Sciences, Kyushu University
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HIGUCHI Ryuichi
Graduate School of Pharmaceutical Sciences, Kyushu University
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YAMADA Koji
Faculty of Engineering, Saitama University
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Miyamoto Tomofumi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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INAGAKI Masanori
Graduate School of Pharmaceutical Sciences, Kyushu University
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Higuchi Ryuichi
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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Higuchi Ryuichi
Faculty Of Pharmaceutical Sciences Kyushu University
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Yamada K
Graduate School Of Pharmaceutical Sciences Kyushu University
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MIYAMOTO Tomofumi
Faculty of Pharmaceutical Sciences, Kyushu University
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KISA Fumiaki
Faculty of Pharmaceutical Sciences, Kyushu University
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Miyamoto T
Graduate School Of Pharmaceutical Sciences Kyushu Univ.
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Yamada Katsuya
Graduate School Of Pharmaceutical Sciences Nagoya City University
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Kisa Fumiaki
Faculty Of Pharmaceutical Sciences Kyushu University
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Inagaki Masanori
Faculty Of Pharmaceutical Sciences Kyushu University
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Yamada Kenji
Tokyo University Of Pharmacy And Life Sciences School Of Pharmacy
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Maruta Tomoki
Graduate School Of Pharmaceutical Sciences Kyushu University
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Ito Masaki
The First Department Of Internal Medicine Mie University School Of Medicine
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Inagaki M
Graduate School Of Pharmaceutical Sciences Chiba University
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Yamada Koji
Faculty Of Engineering Saitama University
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