Effects of Hsp90 inhibitors, geldanamycin and its analog, on ceramide metabolism and cytotoxicity in PC12 cells
スポンサーリンク
概要
- 論文の詳細を見る
- 2012-10-01
著者
-
Kasuga Masato
Department Of Hospital Pharmacy School Of Medicine Kobe University
-
OKUMA Yasunobu
Departmen of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University
-
野村 靖幸
北海道大学・大学院薬学研究科医療薬学講座薬理学分野
-
Nomura Yasuyuki
Dep. Of Pharmacotherapeutics Yokohama Coll. Of Pharmacy Jpn
-
SAITO Takeshi
Laboratory of Environmental Biology, Hokkaido University School of Medicine
-
Murayama T
Laboratory Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Chiba University
-
Murayama Toshihiko
Laboratory Of Chemical Pharamacology Graduate School Of Pharmaceutical Sciences Chiba University
-
Murayama Toshihiko
Lab. Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Chiba Univ. Jpn
-
Kaneko Masayuki
Department Of Dental Radiology Health Sciences University Of Hokkaido
-
Toyomura Kaori
Laboratory Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Chiba University
-
Nomura Yasuyuki
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Hokkaido University
-
Matsumoto Ikiru
Laboratory Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Chiba University
-
Saito Takeshi
Faculty Of Pharmaceutical Sciences Kyushu University
-
Nakamura Hiroyuki
Laboratory Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Chiba University
-
Okuma Yasunobu
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Chiba Institute Of Science
-
Kaneko Masayuki
千葉科学大学
-
EMORI Syunsuke
Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical, Sciences, Chiba University
-
KATO Erina
Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical, Sciences, Chiba University
-
Kato Erina
Laboratory Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Chiba University
-
Emori Syunsuke
Laboratory Of Chemical Pharmacology Graduate School Of Pharmaceutical Sciences Chiba University
-
Saito Takeshi
Laboratory Of Environmental Biology Hokkaido University School Of Medicine
-
Kaneko Masayuki
Department of Cardiology, Cardiovascular Center, Oita Oka Hospital
関連論文
- 脳内免疫機構に関与するレプチンの役割とレプチン受容体機構
- P-11 Eupafolin のα_2 受容体への作用 : 血圧および血管平滑筋収縮への影響
- 老化促進モデルマウスSAMP8、SAMP10の記憶障害・情動障害と脳の生化学的異常
- PC12細胞におけるS-ニトロソシステインによる[Ca^]_iの上昇
- PC12細胞からのノルアドレナリン放出-低分子量G蛋白ARFの関与
- P-12 黄蓍成分 pterocarpan の血管平滑筋細胞増殖能に対する作用
- P-44 老化促進モデルマウス SAMP8 の記憶学習障害に対するハマボウフウの改善効果
- Molecular Pathopharmacology of 5-HT_ Receptors and the RNA Editing in the Brain
- 功労賞受賞 大関正弘氏の業績(紹介)
- 序文
- 衝動性と5HT2A受容体遺伝子多型との関連性 : Go/Nogo 課題を用いた検討
- 学術貢献賞受賞 山内 卓氏の業績
- 薬学部における6年制と4年制学科の共存について
- 小胞体の変性タンパク質処理系を介するニューロン死防御作用
- 小胞体ストレス応答系と神経細胞死制御 : 序文
- 小胞体の変性タンパク質処理系を介するニューロン死防御作用
- 小胞体ストレス応答系と神経細胞死制御 : 序文
- Preconditioning処置は,虚血処置によってもたらされるラット大脳皮質のペヌンブラ領域における神経細胞死をAktの持続的な活性を介して抑制する(生化学)
- 生命科学の研究と教育
- 奨励賞受賞 上原 孝氏の業績
- ニューロン死に対する 4-phenylbutyrate の防御作用機構
- ニューロン死制御機構 : グリア細胞の脳虚血応答因子の関与
- JJP発展のためにご協力を
- 脳老化促進マウスの学習・記憶力及び免疫機能低下のaFGFによる防止
- Knock-down of Sorcin Induces Up-regulation of MDR1 in HeLa Cells(Molecular and Cell Biology)
- Effects of carvedilol on MDR1-mediated multidrug resistance : comparison with verapamil
- Deficits in learning ability and aging of skin in both strains of senescence-accelerated mouse (SAM) P8 and P10 : neuropathological, neurochemical, histological and pharmacological analysis(Chemical & Pharmacological study)
- Age-Related Alterations in the Expression of Glial Cell Line-Derived Neurotrophic Factor in the Senescence-Accelerated Mouse Brain
- Depressive Behavior and Alterations in Receptors for Dopamine and 5-Hydroxytryptamine in the Brain of the Senescence Accelerated Mouse (SAM)-P10
- 老化促進モデルマウスSAMP10における空間認知/情動障害と神経化学的異常
- MDR1 T-129C Polymorphism can be Predictive of Differentiation, and Thereby Prognosis of Colorectal Adenocarcinomas in Japanese(Biopharmacy)
- MDR1, MRP1 and MRP2 Genotypes and In Vitro Chemosensitivity in Japanese Patients with Colorectal Adenocarcinomas
- Different Contribution of CYP2C19 in the in Vitro Metabolism of Three Proton Pump Inhibitors
- Pancreatic Arteriovenous MalformationCombined with Portal Thrombosis
- MDR1 Haplotype Frequencies in Japanese and Caucasian, and in Japanese Patients with Colorectal Cancer and Esophageal Cancer
- MDR1 C3435T Polymorphism Is Predictive of Later Onset of Ulcerative Colitis in Japanese(Biopharmacy)
- Japanese case of hepatitis B virus genotypes C/D hybrid
- FRS-072 PDK-1 is Required for Regulation of Cell Size and Beta-adrenergic Response in the Hearts(Heart Failure Research (M) FRS15,Featured Research Session,The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Helicobacter pylori-negative peptic ulcer in Japan : which contributes most to peptic ulcer development, Helicobacter pylori, NSAIDs or stress?
- Effect of Therapeutic Moderate Hypothermia on Multi-drug Resistance Protein 1-Mediated Transepithelial Transport of Drugs
- Comparison of Synthetic DNA Templates with Authentic cDNA Templates in Terms of Quantification by Real-Time Quantitative Reverse Transcription Polymerase Chain Reaction(Analytical Biochemistry)
- Effects of Acid and Lactone Forms of Eight HMG-CoA Reductase Inhibitors on CYP-Mediated Metabolism and MDR1-Mediated Transport
- Role of Hepatic STAT3 in the Regulation of Lipid Metabolism
- Centrally Applied Nitric Oxide Donors Inhibit Vagally Evoked Rat Gastric Acid Secretion: Involvement of Sympathetic Outflow
- Effects of Polymorphisms of MDR1, MRP1, and MRP2 Genes on Their mRNA Expression Levels in Duodenal Enterocytes of Healthy Japanese Subjects(Biopharmacy)
- MDR1-Mediated Interaction of Digoxin with Antiarrhythmic or Antianginal Drugs
- Factors Influencing the Prediction of Steady State Concentrations of Digoxin
- Interaction of Docetaxel ("Taxotere") with Human P-Glycoprotein
- P-gp誘導 Caco-2 細胞 : P-gp高感度 Assay System の構築
- Effects of Various Storage Conditions and Alterations of Antioxidant Contents on Chromatic Aberration of Hydroquinone Ointment(Biopharmacy)
- Effect of Serum Triglyceride Concentration on the Fluctuation of Whole Blood Concentration of Cyclosporin A in Patients
- Activation of Ceramidase and Ceramide Kinase by Vanadate via a Tyrosine Kinase–Mediated Pathway
- PROSPECT OF ENDOSCOPIC MUCOSAL RESECTION FOR EARLY GASTRIC CANCER : OUR DEVICES IN INSULATED-TIP ELECTROSURGICAL KNIFE METHOD
- N-Acetyltransferase 2 Genotype-Related Sulfapyridine Acetylation and Its Adverse Events
- Optimal Dose of Omeprazole for CYP2C19 Extensive Metabolizers in Anti-Helicobacter pylori Therapy : Pharmacokinetic Considerations
- ARGON PLASMA COAGULATION FOR TREATMENT OF HEMORRHAGIC RADIATION GASTRODUODENITIS
- N-Acetyltransferase 2 Genotype Correlates with Sulfasarazine Pharmacokinetics after Multiple Dosing in Healthy Japanese Subjects
- Sufficient effect of 1-week omeprazole and amoxicillin dual treatment for Helicobacter pylori eradication in cytochrome P450 2C19 poor metabolizers
- HILA-DQB1 locus and the development of atrophic gastritis with Helicobacter pylori infection
- Pharmaceutical and Clinical Assessment of Hydroquinone Ointment Prepared by Extemporaneous Nonsterile Compounding
- Correlation Between Decrease in Protein Levels of Ubiquitin Ligase HRD1 and Amyloid-β Production
- TEK/Tie2 Is a Novel Gene Involved in Endoplasmic Reticulum Stress
- A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin.
- Alteration of Leptin-Induced STAT3 Activation in the Brain of Senescence-Accelerated Mouse (SAM) P8(Pharmacology)
- Aspirin and Sodium Salicylate Protect Brain Cell Death Against Endoplasmic Reticulum Stress
- Possible Role of Interleukin-6 in PC12 Cell Death Induced by MPP^+ and Tetrahydroisoquinoline
- Cholecystokinin Inhibits Food Intake Independent of Interleukin-1β Expression in the Brain(Pharmacology)
- Pancreatic β Cell Mass Preserved in Heterozygous PDK1 Knockout Mice
- Age-Related Alterations in the Expression of Glial Cell Line-Derived Neurotrophic Factor in the Senescence-Accelerated Mouse Brain
- Reduced Insulin Signaling and Endoplasmic Reticulum Stress Act Synergistically to Deteriorate Pancreatic β Cell Function
- Novel Functions of Ubiquitin Ligase HRD1 With Transmembrane and Proline-Rich Domains
- A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes
- The Age-Related Degeneration of Oligodendrocytes in the Hippocampus of the Senescence-Accelerated Mouse (SAM) P8 : A Quantitative Immunohistochemical Study(Pharmacology)
- Manganese Superoxide Dismutase Is Induced by Endoplasmic Reticulum Stress through IRE1-Mediated Nuclear Factor (NF)-κB and AP-1 Activation(Biochemistry/Molecular Biology)
- Activation Signal of Nuclear Factor-κB in Response to Endoplasmic Reticulum Stress is Transduced via IRE1 and Tumor Necrosis Factor Receptor-Associated Factor 2
- Extracellular Signal Regulated Protein Kinase and c-Jun N-Terminal Kinase are Involved in m1 Muscarinic Receptor-Enhanced Interleukin-2 Production Pathway in Jurkat Cells
- Involvement of N-Type Voltage-Activated Ca^ Channels in the Release of Endogenous Noradrenaline from the Isolated Vascularly Perfused Rat Stomach
- Centrally Applied Bombesin Increases Nerve Activity of Both Sympathetic and Adrenal Branch of the Splanchnic Nerves
- SYMPATHO-ADRENOMEDULLARY SYSTEM-MEDIATED CENTRAL REGULATION OF GASTRIC FUNCTION : ROLES OF CENTRAL NEUROTRANSMITTER CANDIDATES
- Senescence-Accelerated Mouse (SAM) as an Animal Model of Senile Dementia: Pharmacological, Neurochemical and Molecular Biological Approach
- TEK/Tie2 Is a Novel Gene Involved in Endoplasmic Reticulum Stress
- DEVELOPMENT OF REGIONAL ACTIVITIES OF 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHOHYDROLASE AND CARBONIC ANHYDRASE IN THE RAT BRAIN : INFLUENCE OF 6-HYDROXYDOPA
- 6-HYDRXYDOPA-INDUCED STIMULATION OF ORNITHINE DECARBOXYLASE ACTIVITY IN THE DEVELOPING RAT BRAIN
- THE EFFECT OF PIPERIDINE AND PIPECOLIC ACID ON HIGH POTASSIUM-INDUCED RELEASE OF NORADRENALINE, SEROTONIN AND GABA FROM RAT BRAIN SLICES
- INFLUENCE OF PIPERIDINE AND PIPECOLIC ACID ON THE UPTAKE OF MONOAMINES, GABA AND GLYCINE INTO P_2 FRACTIONS OF THE RAT BRAIN AND THE SPINAL CORD
- Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain
- Roles of Muscarinic Acetylcholine Receptors in Interleukin-2 Synthesis in Lymphocytes
- Microinjection of α-Calcitonin Gene-Related Peptide into the Hypothalamus Activates Sympathetic Outflow in Rats
- Activation of Ceramidase and Ceramide Kinase by Vanadate via a Tyrosine Kinase-Mediated Pathway
- Correlation Between Decrease in Protein Levels of Ubiquitin Ligase HRD1 and Amyloid-β Production
- Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer's Disease : Possible Involvement of HRD1, a Novel Molecule Related to Endoplasmic Reticulum Stress, in Alzheimer's Disease
- Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain
- Effects of Hsp90 inhibitors, geldanamycin and its analog, on ceramide metabolism and cytotoxicity in PC12 cells
- Possible Involvement of Ubiquitin Ligase HRD1 Insolubilization in Amyloid .BETA. Generation
- Protective Effects of 4-Phenylbutyrate Derivatives on the Neuronal Cell Death and Endoplasmic Reticulum Stress
- Central cholinergic descending pathway to the dorsal motor nucleus of the vagus in regulation of gastric functions.
- Central site of inhibitory action of bombesin on gastric acid secretion in rats.
- Enhancement of gastric acid output and mucosal blood flow by tripeptide thyrotropin releasing hormone microinjected into the dorsal motor nucleus of the vagus in rats.
- Dual effects on gastric acid secretion of electrical stimulation of anterior parts of the rat hypothalamus.
- Discovery of Synthetic Methoxy-substituted 4-Phenylbutyric Acid Derivatives as Chemical Chaperones