OKUMA Yasunobu | Departmen of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University

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著作論文

Deficits in learning ability and aging of skin in both strains of senescence-accelerated mouse (SAM) P8 and P10 : neuropathological, neurochemical, histological and pharmacological analysis(Chemical & Pharmacological study)
Age-Related Alterations in the Expression of Glial Cell Line-Derived Neurotrophic Factor in the Senescence-Accelerated Mouse Brain
Depressive Behavior and Alterations in Receptors for Dopamine and 5-Hydroxytryptamine in the Brain of the Senescence Accelerated Mouse (SAM)-P10
Centrally Applied Nitric Oxide Donors Inhibit Vagally Evoked Rat Gastric Acid Secretion: Involvement of Sympathetic Outflow
Activation of Ceramidase and Ceramide Kinase by Vanadate via a Tyrosine Kinase–Mediated Pathway
Correlation Between Decrease in Protein Levels of Ubiquitin Ligase HRD1 and Amyloid-β Production
TEK/Tie2 Is a Novel Gene Involved in Endoplasmic Reticulum Stress
Alteration of Leptin-Induced STAT3 Activation in the Brain of Senescence-Accelerated Mouse (SAM) P8(Pharmacology)
Aspirin and Sodium Salicylate Protect Brain Cell Death Against Endoplasmic Reticulum Stress
Possible Role of Interleukin-6 in PC12 Cell Death Induced by MPP^+ and Tetrahydroisoquinoline
Cholecystokinin Inhibits Food Intake Independent of Interleukin-1β Expression in the Brain(Pharmacology)
Age-Related Alterations in the Expression of Glial Cell Line-Derived Neurotrophic Factor in the Senescence-Accelerated Mouse Brain
Novel Functions of Ubiquitin Ligase HRD1 With Transmembrane and Proline-Rich Domains
The Age-Related Degeneration of Oligodendrocytes in the Hippocampus of the Senescence-Accelerated Mouse (SAM) P8 : A Quantitative Immunohistochemical Study(Pharmacology)
Extracellular Signal Regulated Protein Kinase and c-Jun N-Terminal Kinase are Involved in m1 Muscarinic Receptor-Enhanced Interleukin-2 Production Pathway in Jurkat Cells
Involvement of N-Type Voltage-Activated Ca^ Channels in the Release of Endogenous Noradrenaline from the Isolated Vascularly Perfused Rat Stomach
Centrally Applied Bombesin Increases Nerve Activity of Both Sympathetic and Adrenal Branch of the Splanchnic Nerves
SYMPATHO-ADRENOMEDULLARY SYSTEM-MEDIATED CENTRAL REGULATION OF GASTRIC FUNCTION : ROLES OF CENTRAL NEUROTRANSMITTER CANDIDATES
Senescence-Accelerated Mouse (SAM) as an Animal Model of Senile Dementia: Pharmacological, Neurochemical and Molecular Biological Approach
TEK/Tie2 Is a Novel Gene Involved in Endoplasmic Reticulum Stress
DEVELOPMENT OF REGIONAL ACTIVITIES OF 2', 3'-CYCLIC NUCLEOTIDE 3'-PHOSPHOHYDROLASE AND CARBONIC ANHYDRASE IN THE RAT BRAIN : INFLUENCE OF 6-HYDROXYDOPA
6-HYDRXYDOPA-INDUCED STIMULATION OF ORNITHINE DECARBOXYLASE ACTIVITY IN THE DEVELOPING RAT BRAIN
THE EFFECT OF PIPERIDINE AND PIPECOLIC ACID ON HIGH POTASSIUM-INDUCED RELEASE OF NORADRENALINE, SEROTONIN AND GABA FROM RAT BRAIN SLICES
INFLUENCE OF PIPERIDINE AND PIPECOLIC ACID ON THE UPTAKE OF MONOAMINES, GABA AND GLYCINE INTO P_2 FRACTIONS OF THE RAT BRAIN AND THE SPINAL CORD
Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain
Roles of Muscarinic Acetylcholine Receptors in Interleukin-2 Synthesis in Lymphocytes
Microinjection of α-Calcitonin Gene-Related Peptide into the Hypothalamus Activates Sympathetic Outflow in Rats
Activation of Ceramidase and Ceramide Kinase by Vanadate via a Tyrosine Kinase-Mediated Pathway
Correlation Between Decrease in Protein Levels of Ubiquitin Ligase HRD1 and Amyloid-β Production
Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer's Disease : Possible Involvement of HRD1, a Novel Molecule Related to Endoplasmic Reticulum Stress, in Alzheimer's Disease
Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain
Effects of Hsp90 inhibitors, geldanamycin and its analog, on ceramide metabolism and cytotoxicity in PC12 cells
Possible Involvement of Ubiquitin Ligase HRD1 Insolubilization in Amyloid .BETA. Generation
Protective Effects of 4-Phenylbutyrate Derivatives on the Neuronal Cell Death and Endoplasmic Reticulum Stress
Central cholinergic descending pathway to the dorsal motor nucleus of the vagus in regulation of gastric functions.
Central site of inhibitory action of bombesin on gastric acid secretion in rats.
Enhancement of gastric acid output and mucosal blood flow by tripeptide thyrotropin releasing hormone microinjected into the dorsal motor nucleus of the vagus in rats.
Dual effects on gastric acid secretion of electrical stimulation of anterior parts of the rat hypothalamus.
Discovery of Synthetic Methoxy-substituted 4-Phenylbutyric Acid Derivatives as Chemical Chaperones

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