グルタミン酸の醗酵生産とその応用に関する研究(第2報) : グルタミン酸醗酵に於ける酸素要求

概要

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It was found that the relation among oxygen demand, glutamic acid production and oxygen supply was belonged to the type of citric acid fermentation according to SHU's classification. Namely, oxygen supply rate necessary for glutamic acid production should be far in excess of that required to satisfy the oxygen demand for respiration.The rate of oxygen consumption may be expressed by the product of cell concetration and respiratory activity, and the effects of the medium constituents for glutamic acid production on these two factors were as follows : 1. Glucose affected cell concentration in broth, but had practically no effect on respiratory activity.2. Urea was somewhat effective in increasing the above two factors.3. Organic nitrogenous compounds produced considerable accelerating effect on growth and respiration.4. Biotin had great effect on the growth of organism employed but no effect on respiratory activity.An appropriate choice of the organic nitrogenous compounds based on the assimilability test gave good yield of glutamic acid (36.25 mg/ml after 48 hr shaking culture).
社団法人日本生物工学会の論文
1961-05-15