New Antidiabetic Compounds, Mangiferin and Its Glucoside
スポンサーリンク
概要
- 論文の詳細を見る
Mangiferin (MF) and its glucosides (mangiferin-7-O-β-glucoside) (MG) isolated from Anemarrhena asphodeloides Bunge rhizome, were tested for their antidiabetic activity in KK-Ay mice, an animal model of non-insulin-dependent diabetes mellitus (NIDDM). MF and MG lowered the blood glucose level of KK-Ay mice after oral administration. However, no affect on the blood glucose level in normal mice was seen, indicating that MF and MG are useful in treating NIDDM. In addition, MF or MG improved hyperinsulinemia in KK-Ay mice. From these findings, it seems likely that MF and MG exert their its antidiabetic activity by increasing insulin sensitivity.
- 社団法人日本薬学会の論文
- 1998-12-15
著者
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Kato M
Department Of Clinical Nutrition Suzuka University Of Medical Science
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三浦 俊宏
鈴鹿医療科学大学
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Tanigawa Keiichiro
Department Of Clinical Nutrition Suzuka University Medical Science
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Tanigawa Keiichiro
鈴鹿医療科学大学 医療栄養
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Tanigawa Keiichiro
Department Of Clinical Nutrition Suzuka University Of Medical Science And Technology
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Tanigawa Keiichiro
Department Of Clinical Nutrition Suzuka University Of Medical Science Faculty Of Healty Of Science
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Komatsu Yasuhiro
北陸大学 薬 薬物治療
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Tanigawa K
Taiho Pharmaceutical Co. Ltd. Saitama Jpn
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ICHIKI Hiroyuki
Tsumura Central Research Laboratories, Tsumura and Co.
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KUBO Masayoshi
Tsumura Central Research Laboratories, Tsumura and Co.
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KOMATSU Yasuhiro
Tsumura Central Research Laboratories, Tsumura and Co.
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ISHIHARA Eriko
鈴鹿医療科学大学
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Komatsu Y
Tsumura Central Research Laboratories Tsumura And Co.
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Komatsu Y
Central Research Laboratories Tsumura & Co
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Komatsu Yasuhiro
Department Of Serology Kanazawa Medical University
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OKADA Minoru
Tsumura Central Research Laboratories, Tsumura and Co.
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MIURA Toshihiro
Suzuka University of Medical Science
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ISHIHARA Eriko
Suzuka University of Medical Science
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TANIGAWA Keiichiro
Suzuka University of Medical Science
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加藤 昌子
Div. Of Chemistry Fac. And Graduate School Of Sci. Hokkaido Univ.
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OKADA Minoru
Tokyo Crude Drugs Association
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三浦 俊宏
Suzuka University of Medical Science and Technology
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ICHIKI Hiroyuki
Pharmacognosy and Medicinal Resources Research Department, Tsumura and Co.
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Komatsu Yasuhiro
Tsumura Central Research Laboratories Tsumura And Co.
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Kubo Masayoshi
Tsumura Central Research Laboratories Tsumura And Co.
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Kato M
Department Of Pharmacotherapeutics Showa Pharmaceutical University
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Komatsu Y
Department Of Serology Kanazawa Medical University
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Komatsu Y
Kampo And Pharmacognosy Laboratories Tsumura & Co.
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Kako M
Suzuka Univ. Medical Sci. And Technol. Mie Jpn
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Ishihara Eriko
Department Of Clinical Nutrition Suzuka University Of Medical Science
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Ichiki H
Tsumura Central Research Laboratories Tsumura And Co.
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Ichiki Hiroyuki
Tsumura & Co.
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Ichiki Hiroyuki
Pharmacognosy And Medicinal Resources Research Department Tsumura And Co.
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Ichiki Hiroyuki
Central Research Laboratory Kampo And Pharmacognosy Laboratory Tsumura & Co.
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Komatsu Y
Res. Center Eishogen Co. Ltd. Saitama Jpn
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Okada Minoru
Tsumura Central Research Laboratories Tsumura And Co.
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Miura Tsutomu
Research Sections Sanwa Shoyaku Co. Ltd.
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Okada Minoru
Tsumura Central Research Laboratories
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Okada Minoru
Kainpo & Pharmacognosy Laboratory Tsumura & Co.
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KOMATSU YASUHIRO
Tsumura Cantral Research Laboratories
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