Antidiabetic Activity of the Rhizoma of Anemarrhena asphodeloides and Active Components, Mangiferin and Its Glucoside
スポンサーリンク
概要
- 論文の詳細を見る
The antidiabetic activity of the rhizoma of Anemarrhena asphodeloides was investigated in KK-Ay mice, an animal model of genetic type 2 diabetes. The water extract of the rhizoma(AA)(90mg/kg)reduced blood glucose levels from 570±29 to 401±59mg/dl 7h after oral administration(p<0.05)and also tended to reduce serum insulin levels in KK-Ay mice. AA-treated KK-Ay mice had significantly reduced blood glucose levels in an insulin tolerance test. Based on these results, the antidiabetic mechanism of AA may be due to decreased insulin resistance. In addition, the active components of AA were confirmed to be mangiferin and its glucoside.
- 社団法人日本薬学会の論文
- 2001-09-01
著者
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Iwamoto Naoki
鈴鹿医療科学大学
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Iwamoto Naoki
Department Of Clinical Nutrition Suzuka University Of Medical Science
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Iwamoto Naoki
Department Of Clinical Informative Medicine Gifu University Graduate School Of Medicine
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Kato M
Department Of Clinical Nutrition Suzuka University Of Medical Science
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SASAKI HIROSHI
Tsumura Laboratory
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三浦 俊宏
鈴鹿医療科学大学
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ISHIDA Torao
Hi-tech Research Center, Suzuka University of Medical Science
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MIURA Toshihiro
Department of Internal Medicine, School of Medicine, Tokai University
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Tanigawa Keiichiro
Department Of Clinical Nutrition Suzuka University Medical Science
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Tanigawa Keiichiro
鈴鹿医療科学大学 医療栄養
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Seino Yutaka
Department of Cardiology, Kansai Electric Power Hospital
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Tanigawa Keiichiro
Department Of Clinical Nutrition Suzuka University Of Medical Science Faculty Of Healty Of Science
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Seino Y
Department Of Diabetes And Clinical Nutrition Kyoto University Graduate School Of Medicine:kansai El
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Tanigawa K
Taiho Pharmaceutical Co. Ltd. Saitama Jpn
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Tanigawa Keiichiro
Department Of Clinical Nutrition Faculty Of Health Science Suzuka University Of Medical Science
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Kato Masaya
Discovery Research Laboratory Tanabe Seiyaku Co. Ltd.
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Ishida Torao
Hi-tech Res. Center Suzuka Univ. Of Medical Sci.
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ICHIKI Hiroyuki
Tsumura Central Research Laboratories, Tsumura and Co.
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KUBO Masayoshi
Tsumura Central Research Laboratories, Tsumura and Co.
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加藤 眞行
New Drug Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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KATO Motoshi
Department of Clinical Nutrition, Suzuka University of Medical Science
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OKADA Minoru
Tsumura Central Research Laboratories, Tsumura and Co.
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加藤 昌子
Div. Of Chemistry Fac. And Graduate School Of Sci. Hokkaido Univ.
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加藤 昌子
奈良女大院人間文化
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Miura T
Laboratory For Immunopharmacology Of Microbial Products School Of Pharmacy Tokyo University Of Pharm
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Miwa T
The 6th Department Of Internal Medicine School Of Medicine Tokai University
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OKADA Minoru
Tokyo Crude Drugs Association
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三浦 俊宏
Suzuka University of Medical Science and Technology
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ICHIKI Hiroyuki
Pharmacognosy and Medicinal Resources Research Department, Tsumura and Co.
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三浦 俊宏
Department Of Clinical Nutrition Suzuka University Of Medical Science
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Kubo Masayoshi
Tsumura Central Research Laboratories Tsumura And Co.
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Kato M
Department Of Pharmacotherapeutics Showa Pharmaceutical University
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Sasaki Horoshi
Faculty of Agriculture, Tohoku University
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Kako M
Suzuka Univ. Medical Sci. And Technol. Mie Jpn
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Seino Y
Division Of Diabetes And Clinical Nutrition Kansai Electric Power Hospital
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Seino Yutaka
Department Of Cardiology Kansai Electric Power Hospital
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Ichiki H
Tsumura Central Research Laboratories Tsumura And Co.
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Ichiki Hiroyuki
Tsumura & Co.
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Ichiki Hiroyuki
Pharmacognosy And Medicinal Resources Research Department Tsumura And Co.
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Ichiki Hiroyuki
Central Research Laboratory Kampo And Pharmacognosy Laboratory Tsumura & Co.
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Seino Yutaka
Division Of Diabetes And Clinical Nutrition Kansai-denryoku Hospital
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Okada Minoru
Tsumura Central Research Laboratories Tsumura And Co.
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Miura T
Department Of Internal Medicine School Of Medicine Tokai University
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Miura Toshihiro
Department Of Clinical Nutrition Suzuka University Of Medical Science
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Miura Tsutomu
Research Sections Sanwa Shoyaku Co. Ltd.
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Okada Minoru
Tsumura Central Research Laboratories
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Sasaki Hiroshi
Japan Kampo Medicine Manufacturers Association
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Sasaki Hiroshi
Department Of Agricultural Chemistry Faculty Of Agriculture Hokkaido University
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Sasaki Hiroshi
Tsumura Central Research Laboratories Tsumura And Co.
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Okada Minoru
Kainpo & Pharmacognosy Laboratory Tsumura & Co.
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Sasaki Hiroshi
金沢大学 自然科学研究科臨床薬学
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Iwamoto Naoki
Department Of Applied Biological Chemistry Graduate School Of Agriculture Kinki University
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