Antidiabetic Activity of Green Tea (Thea sinensis L.) in Genetically Type 2 Diabetic Mice
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概要
- 論文の詳細を見る
The antidiabetic activity of Thea sinensis was investigated in KK-Ay mice, an animal model of genetically type 2 diabetes with hyperinsulinemia. The water extract of Thea sinensis (green tea cold ext) (100mg/kg body weight) reduced the blood glucose of KK-Ay mice 4 and 8 weeks after repeated administration and tended to decrease the plasma insulin level of KK-Ay mice under similar conditions. However, green tea cold ext did not affect blood glucose levels in normal mice. Green tea cold ext decreased blood glucose levels in an insulin tolerance test. These results suggest that the antidiabetic activity of green tea cold ext is derived, at least in part, from a decrease in plasma insulin, due to decreased insulin resistance.
- 公益社団法人日本薬学会の論文
- 2005-12-01
著者
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MIURA Toshihiro
Department of Internal Medicine, School of Medicine, Tokai University
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Ishida Torao
Department Of Hi-tech Research Center Suzuka University Of Medical Science
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Koike Tomoko
Department Of Clinical Nutrition Suzuka University Of Medical Science
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Koike Tomoko
Department Of Adult Nursing Nursing Science School Of Allied Health Sciences
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Miura Toshihiro
Department Of Clinical Nutrition Suzuka University Of Medical Science
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