Studies on Peptides. LV. Total Synthesis of Porcine Motilin, a Gastric Motor Activity Stimulating Polypeptide
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概要
- 論文の詳細を見る
Synthesis of the docosapeptide corresponding to the newly revised sequence of porcine motilin, a gastric motor activity stimulating polypeptide, was accomplished. Synthetic peptide exhibited characteristic contractile activity patterns of the stomach and the duodenum in dogs, which were quite similar to those of the burst activity of these organs.
- 公益社団法人日本薬学会の論文
- 1975-10-25
著者
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甲斐 啓幸
Research laboratories, Sumitomo Pharmaceuticals Co., Ltd.,
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矢島 治明
Faculty Of Pharmaceutical Sciences Kyoto University
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甲斐 啓幸
Research Laboratories Sumitomo Pharmaceuticals Co. Ltd.
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伊藤 漸
Department Of Surgery Gunma University School Of Medicine
関連論文
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- Synthesis of Amaryllidaceae Alkaloids, (±)-Cherylline and (±)-Latifine
- Studies on Peptides. CXXXVI. : Solution-Phase Synthesis of a 37-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Human Calcitonin Gene-Related Peptide (hCGRP)
- Studies on Peptides. XCIV. Synthesis and Activity of Kyotorphin and Its Analogs
- Studies on Peptides. LXXIX. : By-Products derived from N^α-Protected Tryptophan by Acids
- Studies on Peptides. LXXVIII. Synthesis of the Nonacosapeptide corresponding to the Entire Amino Acid Sequence of Avian Glucagon (Duck)
- Studies on Peptides. LXXVII. Synthesis of the Protected Heptadecapeptide corresponding to Positions 13-29 of Avian Glucagon (Duck)
- Studies on Peptides. LXXIII. Examination of the Methanesulphonic Acid Procedure for the Synthesis of Peptides containing Methionine
- Studies on Peptides. LXX. Synthesis of Two Octadecapeptides corresponding to the Entire Amino Acid Sequence of Camel β-Melanocyte-stimulating Hormones
- Studies on Peptides. LXIX. Selective Removal of Acid Labile α-Amino Protecting Groups with Dilute Sulfonic Acids
- Studies on Peptides. LXIII. Synthesis of the Octacosapeptide Corresponding to Positions 1 through 28 of Porcine Gastric Inhibiting Polypeptide (GIP)
- Studies on Peptides. LXII. Synthesis of the Protected Octadecapeptide corresponding to Positions 26 through 43 of Porcine Gastric Inhibitory Polypeptide (GIP)
- Studies on Peptides. XLIX. Synthesis of the Octadecapeptide corresponding to the Entire Amino Acid Sequence of Porcine β-Melanocyte-stimulating Hormone
- Studies on Peptides. CXLI. : Synthesis of a 42-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Porcine GIP (Glucose-Dependent Insulinotropic Polypeptide)
- Studies on Peptides. CXXXIX. : Solution Synthesis of a 42-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Human Glucose-Dependent Insulinotropic Polypeptide (GIP)
- Studies on Peptides. CXXXIII. : Synthesis and Biological Activity of Galanin, a Novel Porcine Intestinal Polypeptide
- Studies on Peptides. CXXXI. Synthesis of Adrenorphin and Enkephalin Analogs
- SYNTHESIS OF A 42 RESIDUE PEPTIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN GIP
- Studies on Peptides. CL. Syntheses of [D-His^2]-Analogs of Enkephalin and Adrenorphin and Several [D-Arg^2]enkephalin Analogs(Organic,Chemical)
- Studies on Peptides. CXXXIV. : Evaluation of S-1-Adamantylcysteine for Peptide Synthesis
- Studies on Peptides. LXXX. N^G-Mesitylene-2-sulfonylarginine
- Studies on Peptides. LX. Synthesis of the Nonatriacontapeptide corresponding to the Entire Amino Acid Sequence of Bovine Adrenocorticotropic Hormone
- Studies on Peptides. XCVII. Synthesis of Porcine Glu^8-Vasoactive Intestinal Polypeptide (VIP)
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- Studies on Peptides. XXII. Synthesis of the partially Protected Pentadecapeptide related to Monkey and Human β-Melanocyte-stimulating Hormones
- Studies on Peptides. XVI. Regeneration of Lysine from N^ε-Formyllysine by Aqueous Hydrazine or Hydroxylamine and Their Application to the Synthesis of α-Melanocyte-stimulating Hormone
- Studies on Peptides. XV. Synthesis of Prolyltyrosylarginylmethionine, the Tetrapeptide situated within the Amino Acid Sequences of Monkey and Human β-Melanocyte-stimulating Hormones.
- Studies on Peptides. XIV. Synthesis of Lysyl-S-benzylcysteinylalanylglutaminyl-S-benzyl-cysteinylhistidine, a Peptide related to Horse Heart Cytochrome C.
- Studies on Peptides. XII.Synthesis of the Decapeptide corresponding to the C-Terminal Portion of β-Melanocyte-stimulating Hormone
- Studies on Peptides. VI. Synthesis of Three Stereoisomeric Pentapeptides of Histidylphenyl-alanylarginyltryptophylglycine Possessing D-Phenylalanyl-D-arginyl Moiety within the Sequence and Their Melanocyte-stimulating Activities in vitro
- Enzyme Immunoassay of Somatostatin (SS)-like Immunoreactive Substance in Bovine Milk
- Studies on Peptides. CLVI. Synthesis of Second Human Calcitonin Gene-Related Peptide (β-hCGRP) by Application of a New Disulfide-Bonding Reaction with Thallium(III) Trifluoroacetate(Organic,Chemical)
- Studies on Peptides. CXLII. : Synthesis of Des-1-Ala-des-α-amino-Human Calcitonin Gene-Related Peptide
- Synthesis of [27-Tyr]-Cholecystokinin-Pancreozymin (CCK-PZ)
- Studies on Peptides. LVII. Synthesis of the Octadecapeptide corresponding to the Entire Amino Acid Sequence of Equine β-Melanocyte-stimulating Hormone
- Studies on Peptides. LIII. Synthesis of the Docosapeptide Corresponding to the Entire Amino Acid Sequence of Porcine ACTH-Like Intermediate Lobe Peptide (CLIP)
- Studies on Peptides. XLIV. Synthesis of the Basic Trypsin Inhibitor from Bovine Pancreas (Kunitz and Northrop) by the Fragment Condensation Procedure on Polymer Support
- Studies on Peptides. XLIII. Synthesis of Two Protected Peptides Related to the C-Terminal Portion of the Basic Trypsin Inhibitor from Bovine Pancreas (Kunitz and Northrop)
- Studies on Peptides. XLII. Synthesis of the Protected Nonapeptide Corresponding to Positions 29 to 37 of the Basic Trypsin Inhibitor from Bovine Pancreas (Kunitz and Northrop)
- Studies on Peptides. XL. Synthesis of the Protected Dodecapeptide corresponding to Positions 1 to 12 of the Basic Trypsin Inhibitor from Bovine Pancreas (Kunitz and Northrop)
- Studies on Peptides, XXXIX. N-Isobutoxycarbonyl-2-alkoxy-1,2-dihydroquinoline Derivatives, as Coupling Reagents in Peptide Synthesis
- Studies on Peptides. XXXV. Some p-Methoxybenzyloxycarbonyl-Amino Acid Derivatives
- Studies on Peptides. XXXI. Synthesis of Two Model Pentapeptides related to Clostridial Ferredoxin
- Studies on Peptides. XXX. Trichloroethyloxycarbonylhydrazine
- Studies on Peptides. XXIX. p-Methoxybenzyl Mixed Carbonates
- Studies on Peptides. Warning for the Explosive Carbazide Formation during the Direct Preparation of t-Butyl Azidoformate or p-Methoxybenzyl Azidoformate
- Studies on Peptides. XXV. A Convenient Procedure for the Preparation of p-Methoxybenzyl Azidoformate
- Studies on Peptides. CXLVI. : Synthesis of Gln^-Motilin and Examination of Its Immunological Properites
- Studies on Peptides. CXLV. : Synthesis of a 27-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Canine Gastrin-Releasing Polypeptide (cGRP)
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- Studies on Peptides. CXXX. Convenient Procedure for the Reduction of Methionine Sulfoxide
- SYNTHESIS OF A 27-RESIDUE PEPTIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN GASTRIN-RELEASING PEPTIDE (hGRP)
- Studies on Peptides. CV. Synthesis of Chicken Neurotensin
- Synthesis and Biological Activity of 8-L-Ala-Motilin and 8-D-Ala-Motilin
- Studies on Peptides. CLI. Syntheses of Cystine-Peptides by Oxidation of S-Protected Cysteine-Peptides with Thallium(III) Trifluoroacetate(Organic,Chemical)
- Studies on Peptides. CXLIII. : Evaluation of β-Methylaspartate for Peptide Synthesis
- Studies on Peptides. CI. Synthesis of a Wasp Venom, Mastoparan M
- Synthesis of Granuliberin-R and Various Fragment Peptides and Their Histamine-Releasing Activities
- Synthesis of the Dodecapeptide Amide corresponding to the Entire Amino Acid Sequence of Granuliberin-R, a New Frog Skin Peptide from Rana rugosa
- Synthesis of Granuliberin-R, a New Frog Skin Peptide from Rana rugosa
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- Studies on Peptides. CX. Solution Synthesis of the Tetratriacontapeptide Amide corresponding to Positions 1 to 34 of Human Parathyroid Hormone
- Studies on Peptides. CIX. Synthesis of the Octatriacontapeptide Corresponding to Positions 1 to 38 of Human Parathyroid Hormone
- Synthesis of the Nonacosapeptide corresponding to Mammalian Glucagon
- Synthesis of Porcine Motilin and Its D-Phe^1-Analog by the Use of Methanesulfonic Acid
- Synthesis of a Heptacosapeptide Amide corresponding to the Entire Amino Acid Sequence of Chicken Gastrin Releasing Peptide (GRP)
- Synthesis of a Heptacosapeptide Amide corresponding to the Entire Amino Acid Sequence of Gastric Gastrin Releasing Peptide
- Selective Transport of the Salts of Amino Acid Esters through an Organic Liquid Membrane with Antamanide as a Carrier
- Studies on Peptides. CXLVIII. : Application of a New Deprotecting Procedure with Trimethylsilyl Trifluoromethanesulfonate for the Syntheses of Two Porcine Spinal Cord Peptides, Neuromedin U-8 and Neuromedin U-25(Amaryllidaceae)(Organic,Chemical)
- Studies on Peptides. CLXVI. : Solid-Phase Syntheses and Immunological Properties of Fragment Peptides Related to Human Hepatitis B Virus Surface Antigen (HBsAg) and Its Pre-S2 Gene
- Studies on Peptides. CLVII. : Synthesis of a Frog-Skin Peptide, Sauvagine
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- Studies on Peptides. CXXXV. : Preparation of Seven Peptide Fragments for the Synthesis of Human Calcitonin Gene-Related Peptide (hCGRP)
- Studies on Peptides. CXXIV. Solution Synthesis of the Hentetracontapeptide Amide Corresponding to the Entire Amino Acid Sequence of Human Corticotropin Releasing Factor (hCRF)
- Studies on Peptides. CXXIII. Preparations of Nine Peptide Fragments for the Synthesis of Human Corticotropin Releasing Factor (hCRF)
- SYNTHESIS OF A HENTETRACONTAPEPTIDE AMIDE CORRESPONDING TO THE ENTIRE AMINO ACID SEQUENCE OF HUMAN CORTICOTROPIN RELEASING FACTOR (hCRF)
- Studies on Peptides. CXVII. Solution Synthesis of the Tetratetracontapeptide Amide Corresponding to the Entire Amino Acid Sequence of Growth Hormone Releasing Factor, Somatocrinin
- SOLUTION SYNTHESIS OF A TETRATETRACONTAPEPTIDE AMIDE WITH GROWTH HORMONE RELEASING ACTIVITY
- Studies on Peptides. CXXXVIII. : Conventional Solution Synthesis of Bovine Hypothalamic Growth Hormone Releasing Factor (bGRF)
- Studies on Peptides. CXXXVII. : Conventional Solution Synthesis of Porcine Hypothalamic Growth Hormone Releasing Factor (pGRF)
- Further Synthesis of Enkephalinol Analogs containing the Dipeptide Unit Tyr-Arg (Kyotorphin)
- Convenient Procedure for the Preparation of α-Amino Alcohols
- Enkephalin Analogs Containing the Dipeptide Unit Tyr-Arg (Kyotorphin)
- Synthesis of Two Peptides corresponding to α-Endorphin and γ-Endorphin by the Methanesulfonic Acid Deprotecting Procedure
- Synthesis of the Untriacontapeptide corresponding to the Entire Amino Acid Sequence of Human β-Endorphin
- Synthesis of the Protected Octadecapeptide corresponding to the Amino Acid Sequence [14-31] of Human β-Endorphin
- Synthesis of the Pentadecapeptide corresponding to the Entire Amino Acid Sequence of Salmon α-Melanotropin II (α-MSH II)
- Solution Synthesis of a Heptacosapeptide known as Bovine γ_3-Melanotropin (γ_3-MSH)
- Synthesis of the Dodecapeptide Designated as Bovine γ-Melanotropin (γ-MSH)
- Synthesis of the Nonatriacontapeptide corresponding to the Entire Amino Acid Sequence of Dogfish Adrenocorticotropic Hormone (Squalus acantias)
- Studies on Peptides. XLVII. Synthesis of Dogfish Melanocyte-Stimulating Hormone (MSH)
- Studies on Peptides. CLXIV. : Solution-Phase Synthesis of a 36-Residue Peptide Amide Corresponding to the Entire Amino Acid Sequence of Chicken Antral Peptide
- Studies on Peptides. CLX. : Synthesis of a 33-Residue Peptide Corresponding to the Entire Amino Acid Sequence of Human Cholecystokinin (hCCK-33)
- Synthesis of the Nonadecapeptide corresponding to Porcine δ-Endorphin
- Synthesis of the Hexadecapeptide corresponding to Positions 1 through 16 of Porcine Motilin, a Gastric Motor Activity Stimulating Polypeptide
- Studies on Peptides. LV. Total Synthesis of Porcine Motilin, a Gastric Motor Activity Stimulating Polypeptide
- Studies on Peptides. LIV. Synthesis of the Protected Tetradecapeptide corresponding to Positions 9 through 22 of Porcine Motilin, a Gastric Motor Activity Stimulating Polypeptide