Coenzyme Analogs. XI. Synthesis of N-Methyl-and N, N-Dimethylcytidine 5'-Phosphate.

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概要

• 論文の詳細を見る

• Uridine was converted to 2', 3'-O-isopropylidene-5'-O-benzoyluridine and derived to 2', 3'-O-isopropylidene-4-methylthiouridine by successive thiolation and methylation. The latter compound was reacted with either CH_3NH_2 or (CH_3)_2NH to produce 2', 3'-O-isopropylidene-N-methyl- or N, N-dimethylcytidine respectively. N-Methyl- and N, N-dimethylcytidine 5'-phosphate were synthesized by the poly-phosphoric acid method followed by the acidic removal of isopropylidene groups.

• 公益社団法人日本薬学会の論文
• 1962-09-25

著者

• 上田 亨

  Faculty of Pharmaceutical Science, Hokkaido University

• 池田 一芳

  The Center for Instrumental Analysis of Hokkaido University

• 池田 一芳

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 池原 森男

  Faculty Of Pharmaceutical Sciences Osaka University

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