Synthesis of 6-Cyanocytidine and Its Derivatives (Nucleosides and Nucleotides. XX
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概要
- 論文の詳細を見る
Treatment of 5-bromocytidine or its 2', 3', 5'-tri-O-acetate, and 2', 3'-O-isopropylidene derivative with sodium cyanide gave the respective 6-cyanocytidine. Methoxide treatment of the 6-cyano compound gave methyl cytidine-6-carboximidate which was converted to cytidine-6-carboxylic acid. Treatment of 2', 3'-O-isopropylidene-N^4-acetyl-5-bromocytidine with sodium cyanide afforded the O^6,5'-cyclo-N^4-acetylcytidine through the 6-cyanocytidine as the intermediate.
- 社団法人日本薬学会の論文
- 1978-08-25
著者
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上田 亨
Faculty of Pharmaceutical Science, Hokkaido University
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松田 彰
Faculty Of Pharmaceutical Sciences Hokkaido University
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井上 英夫
Faculty of Pharmaceutical Sciences, Hokkaido University
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井上 英夫
北海道大学薬学部
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上田 亨
北海道大学薬学部
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井上 英夫
Faculty Of Pharmaceutical Sciences Hokkaido University
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