PHOSPHOLIPASE D-CATALYZED TRANS-ALKYLPHOSPHORYLATION : A FACILE ONE-STEP SYNTHESIS OF NUCLEOSIDE 5'-ALKYLPHOSPHATES

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概要

• 論文の詳細を見る

• Phospholipase D from <Streptomyces>___- effectively catalyzed the transfer reaction of the alkylphosphoryl residue from alkylphosphorylcholines to the 5'-hydroxyl group of nucleosides regiospecifically in a two-phase system. Thus, various nucleoside 5'-alkylphosphates could be readily prepared in high yields.

• 社団法人日本薬学会の論文
• 1988-12-25

著者

• 上田 亨

  Faculty of Pharmaceutical Science, Hokkaido University

• 上田 亨

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 周東 智

  Research Laboratories Toyo Jozo Co. Ltd

• 今村 茂行

  Research Laboratories, Toyo Jozo Co., Ltd,

• 福川 清史

  Research Laboratories, Toyo Jozo Co., Ltd,

• 今村 茂行

  旭化成ファーマ

• 福川 清史

  Reseach Laboratories Toyo Jozo Co. Ltd.

• 上田 亨

  北海道大学薬学部

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