Degradation of Nucleic Acids with Ozone. IV. Specific Internucleotidic Bond-Cleavage of Ozone-Treated Transfer Ribonucleic Acids with Aniline-acetate
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概要
- 論文の詳細を見る
The treatment of transfer ribonucleic acids (tRNAs) with ozone and subsequent treatment with aniline-acetate (pH 4.5) resulted in the internucleotidic bond cleavage of tRNAs. Sequence analysis of the fragments obtained showed that the internucleotidic bond-cleavage occurred at the guanine residues modified with ozone, and the most susceptible sites were those in consecutive sequences of guanine residues, such as -GpGpGpGp- and -GpGp^m^1Gp-in tRNA^<Pro>.
- 公益社団法人日本薬学会の論文
- 1984-02-25
著者
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上田 亨
Faculty of Pharmaceutical Science, Hokkaido University
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上田 亨
Faculty Of Pharmaceutical Sciences Hokkaido University
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原田 文夫
Virology Division, National Cancer Center Research Institute
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三浦 一伸
Faculty of Pharmaceutical Sciences, Hokkaido University
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神力 就子
北海道工開試
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神力 就子
工技院北海道工業開発試験所
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石崎 紘三
Government Industrial Development Laboratory, Hokkaido
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神力 就子
Government Industrial Development Laboratory, Hokkaido
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上田 亨
北海道大学薬学部
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原田 文夫
Virology Division National Cancer Center Research Institute
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三浦 一伸
Faculty Of Pharmaceutical Sciences Hokkaido University
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