Synthesis of Bredinin from 1-β-D-Ribofuranosyl-5-aminoimidazole-4-carboxamide by a Photo-Reaction

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概要

• 論文の詳細を見る

• Photolysis of 1-β-D-ribofuranosyl-5-aminoimidazole-4-carboxamide (AICA-riboside) gave 2-amino-N-(β-D-ribofuranosyl)malondiamide, which was cyclized by treatment with ethyl orthoformate to furnish 1-β-D-ribofuranosyl-5-hydroxyimidazole-4-carboxamide (bredinin), a potent immunosuppressive nucleoside antibiotic.

• 社団法人日本薬学会の論文
• 1986-09-25

著者

• 上田 亨

  Faculty of Pharmaceutical Science, Hokkaido University

• 上田 亨

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 周東 智

  Research Laboratories Toyo Jozo Co. Ltd

• 福川 清史

  Research Laboratories, Toyo Jozo Co., Ltd,

• 平野 孝夫

  Research Laboratories, Toyo Jozo Co., Ltd.,

• 福川 清史

  Reseach Laboratories Toyo Jozo Co. Ltd.

• 上田 亨

  北海道大学薬学部

• 平野 孝夫

  Research Laboratories Toyo Jozo Co. Ltd.

関連論文

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