Effect of Medium-Chain Triglycerides on Postprandial Concentrations of Remnant-Like Particles in Healthy Men
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概要
- 論文の詳細を見る
A high concentration of remnant-like particles (RLP) has shown to be an arteriosclerosis risk factor that strongly reflects disorders of chylomicron and VLDL metabolism in patients with hyperlipidemia. The purpose of this study was to determine the serum concentrations of RLP-cholesterol after intake of meals containing medium-chain triglycerides (MCT) or long-chain triglycerides (LCT) in 29 healthy men. Test meals were prepared by a nationally registered dietitian as a pilaf containing 10 g of MCT or LCT and commercial clear soup. Blood samples were collected at 0, 2, 3, 4, 6 and 8 h after intake of the test meals. The concentrations of serum triglyceride, chylomicrons, chylomicron-triglyceride, RLP-cholesterol, VLDL-cholesterol, and VLDL-triglyceride after intake of MCT were lower than those after intake of the same amount of LCT. Moreover, the areas under the time-concentration curves of triglyceride, chylomicrons and RLP-cholesterol after intake of MCT were significantly lower than those after intake of LCT. The increases in concentrations of serum insulin and total ketone bodies after intake of MCT were significantly greater than those after intake of LCT. These results suggest that MCT may reduce the risk of coronary arteriosclerotic disease by attenuating the postprandial increase of RLP that is closely correlated with arteriosclerosis.
- 日本油化学会の論文
- 2003-04-01
著者
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NOSAKA Naohisa
The Nisshin OilliO Group, Ltd.
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KASAI Michio
The Nisshin OilliO Group, Ltd.
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KONDO Kazuo
Institute of Environmental Science for Human Life, Ochanomizu University
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Kondo Kazuo
長野県工業技術総合センター 食品技術部門加工食品部
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Kondo Kazuo
Institute Of Environmental Science For Human Life Ochanomizu University
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AOYAMA Toshiaki
Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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OKAZAKI Mitsuko
Kagawa Nutrition University
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Nosaka Naohisa
The Nisshin Oillio Group Ltd.
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Kasai M
The Nisshin Oillio Group Ltd.
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Suzuki Yoshie
The Nisshin Oillio Group Ltd.
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Aoyama Toshiaki
Novelty Materials Research Institute Hannan R&d Center Fuji Oil Co.ltd.
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Aoyama Toshiaki
Division Of Healthcare Science Central Research Laboratory The Nisshin Oillio Group Ltd.
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Kasai Michio
The Nisshin Oillio Group Ltd.
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NOSAKA Naohisa
Division of Healthcare Science, Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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KASAI Michio
Division of Healthcare Science, Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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Igarashi Osamu
Ibaraki Christian University
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SUZUKI Yoshie
Division of Healthcare Science, Research Laboratory, The Nisshin Oillio, Ltd.
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MAKI Hideaki
Division of Healthcare Science, Research Laboratory, The Nisshin Oillio, Ltd.
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INUZUKA Hayato
Tyousei Hospital
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Igarashi O
Department Of Life Science Ibaraki Christian University
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Igarashi O
Ibaraki Christian Univ. Hitachi Jpn
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Igarashi Osamu
Joining And Welding Research Institute Osaka University
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Kojima Keiichi
Division Of Healthcare Science Central Research Laboratory The Nisshin Oillio Group Ltd.
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Kondo K
Institute Of Environmental Science For Human Life Ochanomizu University
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Okazaki M
Kagawa Nutrition Univ.
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Kasai Michio
Division Of Healthcare Science Research Laboratory The Nisshin Oillio Group Ltd.
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Aoyama Toshiaki
Central Res. Lab. The Nisshin Oillio Group Ltd.
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MAKI Hideaki
Division of Healthcare Science Research Laboratory, Nisshin Oil Mills, LTD.
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NOSAKA Naohisa
Division of Healthcare Science Research Laboratory, Nisshin Oil Mills, LTD.
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SUZUKI Yoshie
Division of Healthcare Science Research Laboratory, Nisshin Oil Mills, LTD.
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