Effect of Dietary Alpha-Linolenic Acid on Vascular Reactivity in Aorta of Spontaneously Hypertensive Rats
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概要
- 論文の詳細を見る
Several studies of hypertension have shown that dietary alpha-linolenic acid (ALA) has a blood pressure-lowering effect. In the present study, we investigated the effect of dietary ALA on endothelium-dependent vascular reactivity in six-week-old spontaneously hypertensive rats (SHR). At the end of the feeding period, systolic blood pressure in the ALA group was significantly lower than in the control group. There was no significant difference in endothelium-dependent vasorelaxant response between the two diet groups. There was also no significant inter-group difference in the vascular wall thickness and media-to-lumen ratio. In conclusion, the present findings suggest that the blood pressure-lowering mechanism of dietary ALA does not involve increased sensitivity to NO or a change the in vascular morphology of the aorta.
- 日本油化学会の論文
著者
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TAKEUCHI Hiroyuki
Central Research Laboratory, The Nisshin OilliO Group
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AOYAMA Toshiaki
Central Research Laboratory, The Nisshin OilliO Group
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Aoyama Toshiaki
Division Of Healthcare Science Central Research Laboratory The Nisshin Oillio Group Ltd.
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Aoyama Toshiaki
Central Research Laboratory The Nisshin Oillio Group
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Takeuchi Hiroyuki
Central Research Laboratory Of The Nisshin Oillio Group Ltd.
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Ogawa Akiko
Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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Suzuki Yo
Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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Aoyama Toshiaki
Central Research Laboratory Nisshin Oillio Group
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Aoyama Toshiaki
Central Res. Lab. The Nisshin Oillio Group Ltd.
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Aoyama Toshiaki
Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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