Dietary Supplementation of Gamma-Linolenic Acid Improves Skin Parameters in Subjects with Dry Skin and Mild Atopic Dermatitis
スポンサーリンク
概要
- 論文の詳細を見る
Disruption of the skin barrier function caused by epidermal hyper-proliferation, results in the skin becoming dry and showing high transepidermal water loss (TEWL). Gamma linolenic acid (GLA) is reportedly efficacious for treating TEWL and epidermal hyper-proliferation. In this study, to elucidate the effect of GLA-rich oil on skin function, GLA-containing food was given to adults with dry skin or mild atopic dermatitis and skin parameters were evaluated. In the results, we recognized beneficial effects on the TEWL index. The efficacy of GLA was also demonstrated to be statistically significant especially in subjects with pro-inflammatory features. The results suggest that the mechanism of improvement of skin barrier has been associated with possible generation of anti-inflammatory metabolites from GLA. The clinical physician also confirmed that none of the subjects showed any noteworthy side effects. GLA-enriched food appears to be safe and to improve skin barrier function in subjects with dry skin conditions and mild atopic dermatitis.
- 日本油化学会の論文
著者
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Kondo Kazuo
長野県工業技術総合センター 食品技術部門加工食品部
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Ooyama Katsuhiko
Division Of Healthcare Science Central Research Laboratory The Nisshin Oillio Group Ltd.
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Kojima Keiichi
Central Research Laboratory The Nisshin Oillio Group Ltd.
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Kondo K
Institute Of Environmental Science For Human Life Ochanomizu University
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Aoyama Toshiaki
Central Research Laboratory Nisshin Oillio Group
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Kawamura Asuka
Idemitsu Technofine Co.,Ltd.
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Ooyama Katsuhiko
Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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Kachi Hisanori
Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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Abe Tatsuichirou
Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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Amano Kazutoshi
Idemitsu Technofine Co.,Ltd.
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Aoyama Toshiaki
Central Res. Lab. The Nisshin Oillio Group Ltd.
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