Randomly Interesterified Triacylglycerol Containing Medium- and Long-Chain Fatty Acids Stimulates Fatty Acid Metabolism in White Adipose Tissue of Rats
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概要
- 論文の詳細を見る
We have reported previously that randomly interesterified triacylglycerol containing medium- and long-chain fatty acids in the same glycerol molecule (MLCT) resulted in significantly lower body fat accumulation and higher hepatic fatty acid oxidation than from long-chain triacylglycerol (LCT) in rats. To understand the metabolic changes occurring in white adipose tissue, the fatty acid oxidation and synthesis, and the adipocytokine level were measured in rats fed with MLCT or LCT for 2 weeks. In comparison with LCT, MLCT lowered not only the fatty acid synthase and glycerol-3-phosphate dehydrogenase activities in perirenal adipose tissue, but also the serum insulin and leptin levels, in addition to significantly reducing the body fat accumulation. In contrast, fatty acid oxidation measured as the carnitine palmitoyltransferase activity in the tissue was significantly higher in the MLCT-fed rats than in the LCT-fed rats. It seems that the altered fatty acid metabolism in adipose tissue per se was also responsible for the lower adiposity by dietary MLCT.
- 社団法人 日本農芸化学会の論文
- 2006-12-23
著者
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Wu Jian
Division Of Applied Food Research National Institute Of Health And Nutrition
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Wu Jian
国立健康･栄養研究所 食品機能研究部
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AOYAMA Toshiaki
Division of Healthcare Science Research Laboratory, The Nisshin OilliO, Ltd.
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Kasai M
The Nisshin Oillio Group Ltd.
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Aoyama Toshiaki
Novelty Materials Research Institute Hannan R&d Center Fuji Oil Co.ltd.
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Aoyama Toshiaki
Division Of Healthcare Science Central Research Laboratory The Nisshin Oillio Group Ltd.
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Kasai Michio
The Nisshin Oillio Group Ltd.
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KASAI Michio
Division of Healthcare Science, Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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SHINOHARA Hisami
Division of Healthcare Science, Research Laboratory, The Nisshin OilliO Group, Ltd.
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SHINOHARA Hisami
Central Research Laboratory, The Nisshin OilliO Group, Ltd.
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Shinohara Hisami
Central Research Laboratory The Nisshin Oillio Group Ltd.
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Kasai Michio
Division Of Healthcare Science Research Laboratory The Nisshin Oillio Group Ltd.
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SHINOHARA Hisami
Division of Healthcare Science Research Laboratory, Nisshin Oil Mills, LTD.
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