Effects of Ganoderma lucidum Extracts and Their Constituents on the Spontaneous Beating of Myocardial Cell Sheet in Culture

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概要

• 論文の詳細を見る

• The fruiting bodies of Ganoderma lucidum were extracted successively with haxene, methanol and water, and the effect of these extracts and their constituents on the spontaneous beating of myocardial cell sheet in culture was investigated. The hexane and methanol extracts significantly reduced the beating rate, the latter being stronger in potency. All the three extracts tended to increase the beating amplitude. Of the constituents isolated from the extracts, ganoderic acid SI (1), portensterol (6) and ganodermanontriol (7) significantly increased the beating amplitude. Ganodermanontriol (7) increased the beating amplitude most effectively but it significantly reduced the beating rate.

• 日本生薬学会の論文
• 1991-06-20

著者

• 花岡 美代次

  金沢大学薬学部

• KAKIUCHI Nobuko

  Graduate School of Natural Science and Technology, Kanazawa University

• Nagaoka Takema

  Institute Of Natural Medicine Toyama Medical And Pharmaceutical University

• Hattori Masao

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• HADA SUMITRA

  Research Institute for Wakan-Yaku (Oriental Medicines), Toyama Medical and Pharmaceutical University

• Kikuchi T

  Toyama Medical And Pharmaceutical Univ. Toyama Jpn

• Huang S‐l

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• Kakiuchi N

  Graduate School Of Natural Science And Technology Kanazawa University

• Kakiuchi Nobuko

  Research Institute For Wakan-yaku Toyama Medical And Pharmaceutical University

• Kikuchi Tohru

  Research Institute For Wakan-yaku (oriental Medicines) Toyama Medical And Pharmaceutical University

• Kakiuchi Nobuko

  Graduate School Of Natural Sci. And Technol. Kanazawa Univ.

• 花岡 美代次

  Institute Of Natural Medicine University Of Toyama

• Namba Tsuneo

  Research Institute For Wakan-yaku (oriental Medicine) Toyama Medical And Pharmaceutical University

• Huang Sheng-lun

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• Huang Sheng-lun

  Research Institute For Wakan-yaku (traditional Sino-japanese Medicines) Toyama Medical And Pharmaceu

• KAKIUCHI NOBUKO

  Research Institute for Wakan-Yaku (Oriental Medicines)

• HATTORI MASAO

  Research Institute for Wakan-Yaku (Oriental Medicines)

• KIKUCHI Tohru

  Research Institute for Wakan-Yaku (Oriental Medicine), Toyama Medical and Pharmaceutical University

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