Chemical Transformation of Protoberberines. XIII. A Novel and Efficient Synthesis of Antitumor Benzo[c]phenanthridine Alkaloids, Nitidine and Fagaronine(Organic,Chemical)

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概要

• 論文の詳細を見る

• An efficient synthesis of nitidine (1a).and fagaronine (1c), antitumor 2,3,8,9-tetraoxygenated benzo[c]phenanthridine alkaloids, has been achieved via regioselective C_6-N bond cleavage, followed by consecutive oxy-functionalization and recyclization between the C_6 and C_<13> positions of the starting protoberberines, pseudoberberine (3a) and O-benzyldehydrodiscretine (3b), respectively.

• 社団法人日本薬学会の論文
• 1987-06-25

著者

• 山岸 喬

  Natural Products Laboratory Division Of Medicinal Chemistry And Natural Products School Of Pharmacy

• 山岸 浩

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 花岡 美代次

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 花岡 美代次

  金沢大学薬学部

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Osaka University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 向 智里

  金沢大学薬学部

• 向 智里

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 向 智里

  Faculty Of Pharmaceutical Sciences Osaka University

• 丸谷 真理

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 丸谷 真理

  Faculty Of Pharmaceutical Sciences Kanazawa University

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