A NOVEL SYNTHESIS OF QUINAZOLINEQUINONE AND CARBAZOLEQUINONE THROUGH ANIONIC CYCLOADDITION : ITS APPLICATION TO A SYNTHESIS OF MURRAYAQUINONE A

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概要

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• A novel synthesis of the quinazolinequinone (5) and the carbazolequinone (9) is described. Anionic cycloaddition of the heterocyclic esters (1 and 6) with phenyl β-trimethylsilylvinyl sulfone (2c) afforded the cycloadducts (3 and 7), which were converted to the quinones (5 and 9) via the phenols (4 and 8). This method was applied to a covenient synthesis of murrayaquinone A (10).

• 社団法人日本薬学会の論文
• 1994-02-15

著者

• 平井 秀一

  金沢大薬

• 和田 昭盛

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 花岡 美代次

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Osaka University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 平井 秀一

  Faculty of Pharmaceutical Sciences, Kanazawa University

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