1,6-Dihydro-3 (2H)-pyridinones. VIII. Total Synthesis of (±)-Corynantheidol and Formal Synthesis of (±)-Quinine

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概要

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• cis-3,4-Disubstituted piperidine compounds (2 and 3) were stereoselectively prepared from benzyl 3-(1,3-dioxolan-2-ylmethyl)-1,2,3,6-tetrahydropyridine-1-carboxylate (13) via the ketone (17). A total synthesis of (±)-corynantheidol (4) and a formal synthesis of (±)-quinine (5) have also been achieved from the piperidines 2 and 3,respectively.

• 公益社団法人日本薬学会の論文
• 1983-05-25

著者

• 今西 武

  Faculty Of Pharmaceutical Sciences Osaka University

• 和田 泰明

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 井上 誠

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Osaka University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 井上 誠

  Faculty Of Pharmaceutical Sciences Kanazawa University

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