1,6-Dihydro-3 (2H)-pyridinones. VI. Introduction of an Amidocarbonylmethyl Chain at C-4 of the 1,6-Dihydro-3 (2H)-pyridinone Nucleus via Photochemical [2+2] Cycloaddition Reaction

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概要

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• Photochemical reaction of N-substituted 1,6-dihydro-3 (2H)-pyridinones (1) with vinyl acetate resulted in predominant formation of head-to-tail adducts with small amounts of head-to-head adducts. The head-to-tail adduct derivatives (22 and 30) were transformed into lactones (24 and 34), which were further derived to the 4-N, N-dimethyl-carbamoylmethyl-1,6-dihydro-3 (2H)-pyridinones (2a and 2b, respectively).

• 公益社団法人日本薬学会の論文
• 1983-04-25

著者

• 今西 武

  Faculty Of Pharmaceutical Sciences Osaka University

• 和田 泰明

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 井上 誠

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Osaka University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 井上 誠

  Faculty Of Pharmaceutical Sciences Kanazawa University

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