1,6-DIHYDRO-3 (2H)-PYRIDINONES AS SYNTHETIC INTERMEDIATES. TOTAL SYNTHESIS OF (±)-EBURNAMONINE

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概要

• 論文の詳細を見る

• The allyl alcohol (11) derived from the dihydropyridinone (8) by a few steps was transformed into the ester (15) via the Claisen rearrangement, oxidation, esterification, and then hydrogenation. N-Chlorination of 15 followed by a basic hydrolysis afforded the lactone (3) exclusively which was converted into (±)-eburnamonine (1) by the known sequence.

• 公益社団法人日本薬学会の論文
• 1982-04-25

著者

• 今西 武

  Faculty Of Pharmaceutical Sciences Osaka University

• 井上 誠

  Faculty of Pharmaceutical Sciences, Nagoya City University

• 中井 章

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Osaka University

• 花岡 美代次

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 宮下 賢一

  Faculty of Pharmaceutical Sciences, Kanazawa University

• 宮下 賢一

  Faculty Of Pharmaceutical Sciences Kanazawa University

• 井上 誠

  Faculty Of Pharmaceutical Sciences Kanazawa University

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