7,7-Dimethyltricyclo[3.3.0.0^<2,8>]octan-r-ones as Synthetic Intermediates. V. : An Improved Synthesis of (±)-Pentalenene

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概要

• 論文の詳細を見る

• Improved synthetic routes to (±)-pentalenene (1) and (±)-9-epipentalenene (6) were developed. Intramolecular alkylation of a tricyclic halo ester (7), obtained from 3,by treatment with lithium hexamethyldisilazide in tetrahydrofuran gave 14 and 15 in a ratio of 74 : 26. Compound 14 was successfully converted into the key intermediate (16) for (±)-1. On the other hand, catalytic hydrogenation of 8 afforded 20,a key intermediate for (±)-6,along with 16 (20 : 16=86 : 14).

• 公益社団法人日本薬学会の論文
• 1990-05-25

著者

• 今西 武

  Faculty Of Pharmaceutical Sciences Osaka University

• 田中 徹明

  Faculty of Pharmaceutical Sciences, Osaka University

• 岩田 宙造

  Faculty of Pharmaceutical Sciences, Osaka University

• 今西 武

  大阪大学大学院薬学研究科

• 岩田 宙造

  阪大院薬

• 田中 徹明

  阪大院薬

• 田中 徹明

  Faculty Of Pharmaceutical Sciences Osaka University

• Tanaka T

  Kvushu Univ. Fukuoka Jpn

• 山下 正行

  Faculty of Pharmaceutical Sciences, Osaka University

• 広川 美視

  Faculty of Pharmaceutical Sciences, Osaka University

• Tanaka T

  Osaka Univ. Osaka Jpn

• 岩田 宙造

  Faculty Of Pharmaceutical Sciences Osaka University

• Imanishi Takeshi

  Graduate Shool Of Pharmaceutical Sciences Osaka University

• 広川 美視

  Dainippon Pharmaceutical Co. Ltd.

• Imamura T

  Faculty Of Pharmaceutical Sciences Osaka University

• 山下 正行

  Faculty Of Pharmaceutical Sciences Osaka University

• 広川 美視

  Faculty Of Pharmaceutical Sciences Osaka University

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