Studies on Azasteroids and Related Compounds. III. On the Cyclodehydration of Cyclic Ketone and β-Aminoester

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概要

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• With additional identification of two products (V) and (VI) from the reaction between β-aminoester (I) and 2-tetralone, and with results of the reactions hitherto investigated, we proposed the whole aspect of the reaction between β-aminoester and cyclic ketone, as possibly yielding at least nine products. And as the extension to 14-azasteroid syntheses, it was examined the reactions between ethyl 2-pyrrolidine- and 2-piperidine-acetates with 3,4-dihydro-6-methoxy-1H-naphthalen-2-one to afford 1,2,3,5,6,11,12,12a-octahydro-8-methoxynaphth [2,1-e] indolizin-11-one (XVIIIa) and 1,2,3,4,6,7,13,13a-octahydro 9-methoxy-12H-naphtho [1,2-c] quinolizin-12-one (XVIIIb) as expected, besides two other products in each case.

• 公益社団法人日本薬学会の論文
• 1968-09-25

著者

• 岩田 宙造

  Faculty of Pharmaceutical Sciences, Osaka University

• 堀井 善一

  Faculty Of Pharmaceutical Sciences Josai University

• 堀井 善一

  Faculty Of Pharmaceutical Sciences Osaka University

• 岩田 宙造

  Faculty Of Pharmaceutical Sciences Osaka University

• 二宮 一弥

  Faculty of Pharmaceutical Sciences, Osaka University

• 森川 浩一

  Faculty of Pharmaceutical Sciences, Osaka University

• 二宮 一弥

  阪大薬:(現)神戸女子薬科大学

• 森川 浩一

  Faculty Of Pharmaceutical Sciences Osaka University

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