Synthetic Studies on Acorane-Alaskane Sesquiterpenes. II. : Total Synthesis of (±)-Acorenone

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概要

• 論文の詳細を見る

• The metal-ammonia reduction of the cyclopenta[c]benzofuran derivative (2b) afforded a mixture of 4-epi-β-acorenol (5), a disubstituted olefin (8) as the main product, and a perhydro compound (9). Compound 8 was converted to 5 via the exo-diene (15). Dehydration of 5 afforded the 4-epi-β-acoradiene (6), selective reduction of which gave the monoolefin (7), and then the allylic oxidation of 7 gave (±)-acorenone (3) in good yield.

• 公益社団法人日本薬学会の論文
• 1988-05-25

著者

• 山田 稔

  Faculty Of Pharmaceutical Sciences Osaka University

• 田中 徹明

  Faculty of Pharmaceutical Sciences, Osaka University

• 岩田 宙造

  Faculty of Pharmaceutical Sciences, Osaka University

• 前崎 直容

  Faculty of Pharmaceutical Sciences, Osaka University

• 中村 静夫

  Faculty Of Pharmaceutical Sciences Osaka University

• 岩田 宙造

  阪大院薬

• 前崎 直容

  阪大院薬

• 田中 徹明

  阪大院薬

• 田中 徹明

  Faculty Of Pharmaceutical Sciences Osaka University

• Tanaka T

  Kvushu Univ. Fukuoka Jpn

• Tanaka T

  Osaka Univ. Osaka Jpn

• 岩田 宙造

  Faculty Of Pharmaceutical Sciences Osaka University

• 篠尾 恭隆

  Faculty of Pharmaceutical Sciences, Osaka University

• 符阪 隆文

  Faculty of Pharmaceutical Sciences, Osaka University

• 符阪 隆文

  Faculty Of Pharmaceutical Sciences Osaka University

• 篠尾 恭隆

  Faculty Of Pharmaceutical Sciences Osaka University

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