SYNTHESIS OF NEW ANTINEOPLASTIC ALKYLIDENECYCLOPENTENONES
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概要
- 論文の詳細を見る
Novel conjugated cyclopentenones, 5-alkylidene-4-hydroxy-2-cyclopentenones (3) and 5-alkylidene-2-chloro-4-hydroxy-2-cyclopentenones (4) were synthesized from 4-tert-butyldimethylsilyloxy-2-cyclopentenone (5) by two different pathways. These new compounds and their synthetic intermediates strongly inhibited L1210 tumor cell growth in vitro.
- 社団法人日本薬学会の論文
- 1985-09-25
著者
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鈴木 正昭
岐阜大工
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杉浦 聡
Teijin Institute For Bio-medical Research
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黒住 精二
帝人生物医学研究所
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羽里 篤夫
帝人生物医学総合研究所
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羽里 篤夫
Institute For Bio-medical Research Teijin Ltd.
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Tanaka T
Kvushu Univ. Fukuoka Jpn
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Tanaka T
Osaka Univ. Osaka Jpn
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田中 利男
Institute oor Bio-medical Research, Teijin Ltd.
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坂内 清
Institute for Bio-medical Research, Teijin Ltd.
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岡村 憲明
Institute for Bio-medical Research, Teijin Ltd.
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真鍋 健次
Institute for Bio-medical Research, Teijin Ltd.
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黒住 精二
Institute for Bio-medical Research, Teijin Ltd.
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杉浦 聡
Institute for Bio-Medical Research, Teijin Ltd.
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鈴木 正昭
Department of Chemistry, Nagoya University
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野依 良治
Department of Chemistry, Nagoya University
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野依 良治
Department Of Chemistry Nagoya University
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岡村 憲明
Institute For Bio-medical Research Teijin Ltd.
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坂内 清
Institute For Bio-medical Research Teijin Ltd.
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鈴木 正昭
Department Of Chemistry Division Of Material Sciences Graduate School Of Natural Science And Technol
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真鍋 健次
帝人株式会社 生物医学総合研究所
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