A New and Known Cytotoxic Aryltetralin-Type Lignans from Stems of Bursera graveolens

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概要

• 論文の詳細を見る

• A new 4α-aryltetralin-type lignan called burseranin (1) and a known analogous lignan picropolygamain (2) were isolated along with known triterpenes, lupeol and epi-lupeol from the methanol extract of stems of Bursera graveolens, which showed a remarkable inhibitory activity against human HT1080 fibrosarcoma cells. The whole structure of 1 was established based on combined spectral studies and the absolute structure for 2 was first confirmed by CD spectral evidence. In addition, cytotoxic activities of the stem (methanol) extract and its components are evaluated in this paper.

• 公益社団法人日本薬学会の論文
• 2005-02-01

著者

• MURATA JIN

  Botanical Gardens, Graduate School of Sciences, the University of Tokyo

• IINUMA Munekazu

  Gifu Pharmaceutical University

• Murata Jin

  Botanical Gardens Koishikawa Graduate School Of Sci. The Univ. Of Tokyo

• 田中 利男

  帝人株式会社 医薬岩国製造所

• NAKANISHI Tsutomu

  Faculty of Pharmaceutical Sciences,Setsunan University

• INADA Akira

  Faculty of Pharmaceutical Sciences,Setsunan University

• MURATA Hiroko

  Faculty of Pharmaceutical Sciences,Setsunan University

• INATOMI Yuka

  Faculty of Pharmaceutical Sciences,Setsunan University

• Oku Naoto

  University Of Shizuoka School Of Pharmaceutical Sciences

• Shigeta Kaori

  Faculty Of Pharmaceutical Sciences Setsunan University

• TANAKA Toshiyuki

  Gifu Prefectural Institute of Health and Environmental Sciences

• Iinuma Munekazu

  Dep. Of Bioactive Molecules Pharmacognosy Gifu Pharmaceutical Univ.

• Iinuma M

  Gifu Pharmaceutical University

• Iinuma Munekazu

  岐阜薬科大学

• Iinuma M

  城西大学薬学部

• Tanaka Toshiyuki

  Gifu Pharmaceutical Univ.

• Tanaka T

  Kvushu Univ. Fukuoka Jpn

• Murata Hiroko

  東海大学 農学研究科

• Tanaka T

  Osaka Univ. Osaka Jpn

• Murata Hiroko

  Faculty Of Human Life Science Osaka City University

• Tanaka Toshiyuki

  Gifu Prefectrual Inst. Health And Environmental Sci. Gifu Jpn

• IIDA Naoki

  Faculty of Pharmaceutical Sciences, Setsunan University

• FARRERA Miguel

  Escula Biologia, UNICACH

• TAJIMA Shogo

  University of Shizuoka School of Pharmaceutical Sciences

• Iinuma Munekazu

  Gifu Prefectural Institute Of Health And Environment

• Iinuma Munekazu

  Gifu Prefectural Institute Of Health And Environmental Sciences

• Iwashima Akio

  Kyoto Prefectural University of Medicine

• Inada A

  Fac. Of Pharmaceutical Sciences Setsunan Univ.

• Murata Jin

  Botanical Garden Graduate School Of Science University Of Tokyo

• Inada Akira

  Faculty Of Pharmaceutical Sciences Setsunan University

• Farrera Miguel

  Escula Biologia Unicach

• Haramoto Mari

  Graduate School Of Comprehensive Scientific Research Program In Biological System Sciences Prefectur

• Murata H

  Okayama Univ. Okayama Jpn

• Nakanishi T

  Graduate School Of Science Nagoya University

• Nakanishi Tsutomu

  Fac. Of Pharmaceutical Sciences Setsunan Univ.

• Murata Hiroko

  Division Of Virology Department Of Infectious Diseases Osaka Prefectural Institute Of Public Health

• Murata J

  Botanical Gardens Graduate School Of Science The University Of Tokyo

• Tanaka Toshiyuki

  Gifu Pharmaceutical University

• 田中 徹明

  Osaka Univ. Osaka Jpn

• Murata J

  Botanical Gardens Graduate School Of Sciences The University Of Tokyo

• Iinuma Munekazu

  Gifu Pharmaceutical Univ.gifu Jpn

• Nakanishi T

  Fac. Of Pharmaceutical Sciences Setsunan Univ.

• Oku Naoto

  University Of Shizuoka Graduate School Of Pharmaceutical Sciences

• Tanaka Terumichi

  Division Of Bioscience And Biotechnology Department Of Ecological Engineering Toyohashi University O

• Nakanishi Tsutomu

  Faculty Of Pharmaceutical Sciences Setsunan University

• Maruyama Hiroe

  Nagaragawa Research Center Api Company Limited

• Nakanishi Tsutomu

  Faculty Of Engineering Miyazaki University

• Inatomi Yuka

  Faculty of Pharmaceutical Sciences, Setsunan University

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