Gnetol as a Potent Tyrosinase Inhibitor from Genus Gnetum(Biochemistry & Molecular Biology)

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概要

• 論文の詳細を見る

• Gnetol (2, 3', 5', 6-tetrahydroxy-trans-stilbene), a naturally occurring compound particularly found in the genus Gnetum, had a strong inhibitory effect on murine tyrosinase activity. Gnetol (IC_<50>, 4.5 μM) was stronger than kojic acid (IC_<50>, 139 μM) as a standard inhibitor for murine tyrosinase activity. Moreover, gnetol significantly suppressed melanin biosynthesis in murine B16 melanoma cells.

• 社団法人日本農芸化学会の論文
• 2003-03-23

著者

• IINUMA Munekazu

  Gifu Pharmaceutical University

• TANAKA Toshiyuki

  Gifu Prefectural Institute of Health and Environmental Sciences

• ILIYA Ibrahim

  Gifu Pharmaceutical University

• Iinuma Munekazu

  Dep. Of Bioactive Molecules Pharmacognosy Gifu Pharmaceutical Univ.

• Iinuma M

  Gifu Pharmaceutical University

• Iinuma Munekazu

  岐阜薬科大学

• Iinuma M

  城西大学薬学部

• Tanaka Toshiyuki

  Gifu Pharmaceutical Univ.

• Nozawa Yoshinori

  Gifu International Institute of Biotechnology

• Tanaka T

  Osaka Univ. Osaka Jpn

• Ohguchi Kenji

  Gifu International Institute of Biotechnology

• AKAO Yukihiro

  Gifu International Institute of Biotechnology

• Ito Tetsuro

  Gifu Prefectural Institute of Health and Environmental Sciences

• Ito Tetsuro

  Laboratory of Pharmacognosy, Gifu Pharmaceutical University

• Ito T

  Dep. Of Bioactive Molecules Pharmacognosy Gifu Pharmaceutical Univ.

• Akao Y

  Gifu International Institute Of Biotechnology

• Nozawa Y

  Gifu International Institute Of Biotechnology

• MATSUMOTO Kenji

  Gifu International Institute of Biotechnology

• Iliya I

  Gifu Pharmaceutical University

• Iliya Ibrahim

  Gifu Pharmaceutical Univ. Gifu Jpn

• Tanaka Toshiyuki

  Gifu Prefectrual Inst. Health And Environmental Sci. Gifu Jpn

• Iinuma Munekazu

  Gifu Prefectural Institute Of Health And Environment

• Araki Yoko

  Nagaragawa Res. Center Api Co. Ltd.

• Araki Yoko

  Nagaragawa Research Center Api Co. Ltd.

• Matsumoto K

  Gifu International Institute Of Biotechnology

• Matsumoto Keiji

  Department Of Orthopaedic Surgery Shiga University Of Medical Science

• Tanaka Toshiyuki

  Gifu Pharmaceutical University

• Ito Tetsuro

  Department Of Bioactive Molecutes Pharmacognosy Gifu Pharmaceutical University

• Ito T

  Gifu Prefectrual Inst. Health And Environmental Sci. Kakamigahara Jpn

• Iinuma Munekazu

  Gifu Pharmaceutical Univ.gifu Jpn

• Matsumoto K

  Central Research Laboratory Hitachi Ltd.

• Tanaka Terumichi

  Division Of Bioscience And Biotechnology Department Of Ecological Engineering Toyohashi University O

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