Identification of Phenolic Compounds in Aquilaria crassna Leaves Via Liquid Chromatography-Electrospray Ionization Mass Spectroscopy

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概要

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• In this study, we extracted Aquilaria crassna with aqueous ethanol and water and analyzed the extracts via liquid chromatography diode array detection and electrospray ionization mass spectrometry (LC– ESI–MS) methods. Phenolics were separated using semi-micro HPLC and were identified as iriflophenone 3,5-C-β-diglucoside (1), iriflophenone 3-C-β-glucoside (2), mangiferin (3), iriflophenone 2-O-α-rhamnoside (4), genkwanin 5-O-β-primeveroside (5), genkwanin 5-O-β-glucoside (6), genkwanin 4′-methyl ether 5-O-β-primeveroside (7), and genkwanin (8) via a comparison with authentic samples. The collision-induced dissociation (CID)-MS/MS spectra of these polyphenols and the unknown chromatographic peaks were detected using hybrid ion trap time-of-flight (IT-TOF) mass spectrometry. The results of the present study demonstrated that LC–ESI–MS can be useful for the specific quality control of extracts of extracted A. crassna.

• 社団法人　日本食品科学工学会の論文
• 2012-03-01

著者

• Iinuma Munekazu

  Dep. Of Bioactive Molecules Pharmacognosy Gifu Pharmaceutical Univ.

• Iinuma M

  Gifu Pharmaceutical University

• Iinuma Munekazu

  岐阜薬科大学

• Iinuma M

  城西大学薬学部

• Murata Hiroko

  東海大学 農学研究科

• Okano M

  Kitasato Univ. Sagamihara Jpn

• 大村 三男

  Fruit Tree Research Station

• Ito Tetsuro

  Laboratory of Pharmacognosy, Gifu Pharmaceutical University

• Oyama Masayoshi

  Laboratory of Pharmacognosy, Gifu Pharmaceutical University

• Iinuma Munekazu

  Laboratory of Pharmacognosy, Gifu Pharmaceutical University

• Hara Hideaki

  Research And Development Center Santen Pharmaceutical Co. Ltd.

• Omura M

  Okitsu Branch Fruit Tree Research Station Ministry Of Agriculture Forestry And Fisheries

• Omura Mitsuo

  Faculty Of Pharmacy Meijo University

• Akao Y

  Gifu International Institute Of Biotechnology

• Ohtani Mikinobu

  Department Of Urology Instiute Of Clinical Medicine University Of Tsukuba

• Iinuma Munekazu

  Gifu Prefectural Institute Of Health And Environment

• Araki Yoko

  Nagaragawa Res. Center Api Co. Ltd.

• Araki Yoko

  Nagaragawa Research Center Api Co. Ltd.

• Maruyama Hiroe

  Nagaragawa Research Center, API Co., Ltd.

• Murata H

  Okayama Univ. Okayama Jpn

• Onozawa Mizuki

  Cancer Prevenition Division National Cancer Center Research Instiute

• Murata Hiroko

  Division Of Virology Department Of Infectious Diseases Osaka Prefectural Institute Of Public Health

• Ohyama M

  Cancer Prevenition Division National Cancer Center Research Instiute

• Hara H

  (present Address)corporate Planning Dept. Yamanouchi Pharmaceutical Co. Ltd.

• Araki Yoko

  Nagara Res. Center Api Co. Ltd.

• Ito Tetsuro

  Department Of Bioactive Molecutes Pharmacognosy Gifu Pharmaceutical University

• Kakino Mamoru

  Department Of Biofunctional Evaluation Molecular Pharmacology Gifu Pharmaceutical University

• Ito T

  Gifu Prefectrual Inst. Health And Environmental Sci. Kakamigahara Jpn

• KAKINO Mamoru

  Laboratory of Molecular Pharmacology, Gifu Pharmaceutical University

• TAZAWA Shigemi

  Nagaragawa Research Center, Api Company Limited

• HARA Hideaki

  Laboratory of Molecular Pharmacology, Gifu Pharmaceutical University

• Oyama Masayoshi

  Laboratory Of Pharmacognosy Gifu Pharmaceutical University

• Maruyama Hiroe

  Nagaragawa Research Center Api Company Limited

• Tazawa Shigemi

  Nagaragawa Research Center Api Company Limited

• Kakino Mamoru

  Laboratory Of Molecular Pharmacology Gifu Pharmaceutical University

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