Screening of Anti-HIV-1 Activity of North American Plants. : Anti-HIV-1 Activities of Plant extracts, and Active Components of Lethalia vulpina (L.) Hue.

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概要

• 論文の詳細を見る

• Acetone, ethanol, and/or 70% aqueous ethanol extracts (264 extracts) of 84 species of western North American plants were assayed by using the index of HIV-1-induced cytopathogenic effects in MT-4 cells. 80 extracts from 43 species (one lichen and 42 higher plants) in 22 families showed the anti HIV-1 activity, of which, 13 extracts from 9 species, were very active. One of the effective extracts, an acetone extract of Lethalia vulpina (L.) Hue, was chemically investigated. The compounds having the anti HIV-1 activity were identified as vulpinic acid, ergosterol peroxide, and (+)-usnic acid.

• 日本生薬学会の論文
• 1998-12-20

著者

• Murata Jin

  Botanical Gardens Koishikawa Graduate School Of Sci. The Univ. Of Tokyo

• 山崎 勝也

  大阪市立大学医学部生体情報解析学講座

• NAKANISHI Tsutomu

  Faculty of Pharmaceutical Sciences,Setsunan University

• INATOMI Yuka

  Faculty of Pharmaceutical Sciences,Setsunan University

• Lang Frank

  Dep. Of Biology Southern Oregon Univ.

• Yamasaki K

  Faculty Of Pharmaceutical Sciences Teikyo Heisei University

• Yamasaki Katsuhiro

  Osaka Prefectural Institute of Public Health

• Otake Toru

  Osaka Prefectural Institute Of Public Health

• KAWAHATA Takuya

  Osaka Prefectural Institute of Public Health

• Murata Hiroko

  Faculty Of Human Life Science Osaka City University

• NAKANO Masami

  Osaka Prefectural Institute of Public Health

• MORI Haruyo

  Osaka Prefectural Institute of Public Health

• Yamasaki K

  Division Of Medicinal Chemistry Graduate School Of Biomedical Sciences Hiroshima University

• Ohnuki T

  Sankyo Co. Ltd. Tokyo Jpn

• Iwashima Akio

  Kyoto Prefectural University of Medicine

• Otake Toru

  Otemae College Of Nutrition

• Inada A

  Fac. Of Pharmaceutical Sciences Setsunan Univ.

• Inada Akira

  Faculty Of Pharmaceutical Sciences Setsunan University

• Murata H

  Okayama Univ. Okayama Jpn

• Kawahata T

  Division Of Virology Department Of Infectious Diseases Osaka Prefectural Institute Of Public Health

• Nakano M

  Discovery Research Laboratory Tanabe Seiyaku Co. Ltd

• Murata Hiroko

  Division Of Virology Department Of Infectious Diseases Osaka Prefectural Institute Of Public Health

• Nakano Masami

  Faculty Of Pharmaceutical Sciences Setsunan University

• Murata Jin

  Makino Herbarium Faculty Of Science Tokyo Metropolitan University

• Murata J

  Botanical Gardens Graduate School Of Sciences The University Of Tokyo

• LANG Frank.

  Department of Biology, Southern Oregon University

• Nakanishi Tsutomu

  Faculty Of Pharmaceutical Sciences Setsunan University

• Nakanishi Tsutomu

  Faculty Of Engineering Miyazaki University

• Okuda Toru

  Otemae College of Nutrition

• Inatomi Yuka

  Faculty of Pharmaceutical Sciences, Setsunan University

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