抗潰瘍剤レバミピドの開発

スポンサーリンク

概要

• 論文の詳細を見る
• 有機合成化学協会の論文
• 1995-12-01

著者

• 山崎 勝也

  大阪市立大学医学部生体情報解析学講座

• 山崎 勝也

  大阪市立大学 医学部 内視鏡部

• 小松 真

  大塚製薬(株)新薬第三研究所

• 内多 稔

  大塚製薬(株)徳島研究所

• Uchida Masaatsu

  Departments Of Pharmacology Meiji Pharmaceutical University

• Uchida Mihoko

  Department Of Biochemistry Faculty Of Pharmaceutical Sciences Hoshi University

関連論文

• 5-(3-tert-Butylamino-2-hydroxypropoxy)-8-hydroxy-3,4-dihydrocarbostyril Hydrochlorideの合成とそのβ-遮断作用について
• 抗潰瘍剤レバミピドの開発
• Studies on Gastric Antiulcer Active Agents. III. : Synthesis of 1-Substituted 4-(5-Tetrazolyl)thio-1-butanones and Related Compounds
• Studies on Gastric Antiulcer Active Agents. II. : Synthesis of Tetrazole Alkanamides and Related Compounds
• Studies on 2(1H)-Quinolinone Derivatives as Gastric Antiulcer Active Agents. Synthesis and Antiulcer Activities of Optically Active α-Amino Acid Derivatives of 2(1H)-Quinolinone and Oxindole(Medicinal Chemistry,Chemical)
• Studies on 2(1H)-Quinolinone Derivatives as Gastric Antiulcer Active Agents. Synthesis and Antiulcer Activity of the Metabolites of 2-(4-Chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic Acid
• 3-芳香環置換2-(4-Chlorobenzoylamino)propionic Acid誘導体の合成と抗潰瘍作用について
• Studies on 2 (1H)-Quinolinone Derivatives as Gastric Antiulcer Active Agents. 2-(4-Chlorobenzoylamino)-3-[2 (1H)-quinolinon-4-yl] propionic Acid and Related Compounds
• Synthesis of 4-(phenylamino)quinoline-3-carboxamides as a Novel Class of Gastric H^+/K^+-ATPase Inhibitors
• Synthesis and Antiulcer Activity of Optical Isomers of 2-(4-Chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic Acid (Rebamipide)
• Synthesis and Antiulcer Activity of 4-Substituted 8-[(2-Benzimidazolyl)sulfinylmethyl]-1,2,3,4-tetra-hydroquinolines and Related Compounds
• Studies on Proton Pump Inhibitors. III. : Synthesis of 8-[(2-Benzimidazolyl)sulfinylmethyl]-1,2-dihydroquinolines and Related Compounds
• Studies on Proton Pump Inhibitors. II. : Synthesis and Antiulcer Activity of 8-[(2-Benzimidazolyl)-sulfinylmethyl]-1,2,3,4-tetrahydroquinolines and Related Compounds
• Studies on Proton Pump Inhibitors. I. : Synthesis of 8-[(2-Benzimidazoly)sulfinyl]-5,6,7,8-tetrahydroquinolines and Related Compounds
• Edaravone, a Radical Scavenger, May Enhance or Produce Antiproliferative Effects of Fluvastatin, Amlodipine, Ozagrel, GF109203X and Y27632 on Cultured Basilar Artery Smooth Muscle Cells (Pharmacology)
• Synthesis and Antibacterial Activity of the Metabolites of 9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidyl)-5-methyl-1-oxo-1H, 5H-benzo[i, j]quinolizine-2-carboxylic Acid (OPC-7251)
• Anti-HIV-1 Activity of Herbs in Labiatae
• In Vitro Antioxidant Activity of Vietnamese Ginseng Saponin and Its Components
• The Possible Involvement of GABA_A Systems in the Antinarcotic Effect of Majonoside-R2, a Major Constituent of Vietnamese Ginseng, in Mice
• A New Secoiridoid Glucoside from a Malagasy Medicinal Plant, Cassinopsis chapieleri
• Cussosaponins A-E, Triterpene Saponins from the Leaves of Cussonia racemosa, a Malagasy Endemic Plant
• A New ent-Kaurane Diterpenoid Glycoside from the Leaves of Cussonia bojeri, a Malagasy Endemic Plant
• A Novel Preparation Method for Microspheres of Water Soluble Polymers Using Polypropyleneglycol as the Dispersion Medium
• Enzymic Production of Sweet Stevioside Derivatives : Transglucosylation by Glucosidases(Organic Chemistry)
• Synthesis and Absolute Configuration of the Enantiomers of 7-Fluoro-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone (Flosequinan)
• Hydrolyzable tannins and phenylpropanoid from Rafflesia kerrii Meijer (Rafflesiaceae)
• Chemical Constituents of Thai Medicinal Plant, Polyalthia cerasoides
• Pregnane and Pregnane Glycosides from the Malagasy Plant, Cynanchum aphyllum
• Stilbene and 2-Arylbenzofuran Glucosides from the Rhizomes of Schoenocaulon officinale
• Acetylated Triterpene Saponins from the Thai Medicinal Plant, Sapindus emarginatus
• Sweet Pregnane Glycosides from Telosma procumbens
• Major Metabolites of Ginseng Sapogenins formed by Rat Liver Microsomes
• Effects of Particle Size, Helium Gas Pressure and Microparticle Dose on the Plasma Concentration of Indomethacin after Bombardment of Indomethacin-Loaded Poly-L-Lactic Acid Microspheres Using a Helios^ Gun System
• Synthesis of Possible Metabolites of 1-Cyclopropyl-1,4-dihydro-6-fluoro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid (Grepafloxacin, OPC-17116)
• Antioxidative Effect of Sesamol and Related Compounds on Lipid Peroxidation
• 1,6-Asymmetric Induction Utilizing Asymmetric Desymmetrization by Diastereoselective C-O Bond Fission of the 4-Substituted Bicyclic Acetal : Application to a Synthesis of (-)-Frontalin
• Indole Alkaloid Production in Callus Cultures of Uncaria rhynchophylla (MIQ.) MiQUEL
• Relationships between the Particle Velocity and Introduction of Drug-Loaded Microparticles into the Skin in a Microparticulate Bombardment System
• Intranasal Administration of Milnacipran in Rats: Evaluation of the Transport of Drugs to the Systemic Circulation and Central Nervous System and the Pharmacological Effect
• Synthesis of Metabolites of the Cerebroprotecting Agent 7-Hydroxy-1-[[[4-(3-methoxyphenyl)-1-piperazinyl]acetyl]amino]-2,2,4,6-tetramethylindan (OPC-14117)
• Flavonol Glycosides and Phenolics from Leaves of Cordia dichotoma(Natural Medicine Note)
• Screening of Anti-HIV-1 Activity of North American Plants. : Anti-HIV-1 Activities of Plant extracts, and Active Components of Lethalia vulpina (L.) Hue.
• Identification and Quantification of 20(S)-Protopanaxatriol and its 20S, 24S-Epoxide in Human Urine with the Treatment of A1kaline Cleavage after the Ingestion of Sanchi Ginseng, the Roots of Panax notoginseng(三七人参)
• Antimicrobial Activities of Saponins of Pericarps of Sapindus mukurossi on Dermatophytes
• Iridoid Glucosides from a Malagasy Medicinal Plant, Ophiocolea floribunda(Natural Medicine Note)
• A New Secoiridoid Glucoside from a Malagasy Medicinal Plant, Cassinopsis chapieleri
• Iridoid glucosides from Catunaregam tomentosa Tirveng(Natural Medicine Note)
• Chemical Constituents of Beaumontia grandiflora Wall(Natural Medicine Note)
• Chemical Constituents of Thai Medicinal Plant, Diplocyclos palmatus(Natural Medicine Note)
• Chemical Constituents of Thai Medicinal Plant, Polyalthia cerasoides
• Flavonoid glycosides from Acanthus ilicifolius L.(Natural Medicine Note)
• Canthin-6-one alkaloids from callus cultures of Eurycoma longifolia
• A Hemiterpenoid Glucoside from Musa paradisiaca
• New Glucosides from Thai Medicinal Plant, Balanophora latisepala
• Clonal Multiplication of Panax japonicus by Tissue Culture
• Phenolic compounds from leaves of Cassia alata(Natural Medicine Note)
• Lignan glucoside from Syzygium cumini
• C-Glycosyl Flavones from Clinacanthus nutans(Natural Medicine Note)
• Phenylethanoids and Cyclohexylethanoids from Oroxylum indicum

もっと見る 閉じる

スポンサーリンク