Studies on Ergot Alkaloids and Related Compounds. IV. Preparation and Lithium Aluminum Hydride Reduction of Some Vinylogous Lactams.

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概要

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• Condensation of 5-phthalimido-2-tetralone (Ic) and methyl 2-methyl-3-methylaminopropionate (XIV) by the method of Nelson, et al. yielded (IIIc) as a major product and (IVc) as a minor product. The structures of both products were established mainly by comparison of their infrared and ultraviolet spectra with those of several compounds having similar structures. Consequently, it was found that nine vinylogous lactams newly prepared could be classified into two groups, normal vinylogous lactams (IVb, c), (VIIIa, b, c) and cross-conjugated ones (IIIa〜d), (VI), from their spectral data and their behaviors towards lithium aluminum hydride reduction.

• 公益社団法人日本薬学会の論文
• 1962-10-25

著者

• 岩田 宙造

  Faculty of Pharmaceutical Sciences, Osaka University

• 堀井 善一

  School of Pharmacy, Osaka University

• 田村 恭光

  School of Pharmacy, Osaka University

• 岩田 宙造

  School of Pharmacy, Osaka University

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