Efficient Removal of Protecting Groups by a 'Push-Pull' Mechanism. II. Deprotection of O-Benzyltyrosine with a Thioanisole-Trifluoroacetic Acid System without O-to-C Rearrangements
スポンサーリンク
概要
- 論文の詳細を見る
A thioanisole-trifluoroacetic acid (TFA) system was found to deprotect Tyr (Bzl) quantitatively at 25°within 3 hr by a push-pull mechanism without O-to-C rearrangements. This new deblocking system did not completely deprotect Ser (Bzl) and Thr (Bzl), but deprotected Lys (Z) quantitatively.
- 社団法人日本薬学会の論文
- 1980-02-25
著者
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木曽 良明
Department of Medicinal Chemistry, Kyoto Pharmaceutical University
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中村 静夫
Faculty Of Pharmaceutical Sciences Osaka University
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中村 静夫
Faculty Of Pharmaceutical Sciences University Of Tokushima
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木曽 良明
Department Of Medicinal Chemistry Kyoto Pharmaceutical University
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木曽 良明
Faculty of Pharmaceutical Sciences, University of Tokushima
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秋田 正
Faculty Of Pharmaceutical Sciences The University Of Tokushima
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