A SIMPLE DIASTEREOSELECTIVE SYNTHESIS OF CYCLOHEXYLNORSTATINE AND ALLOCYCLOHEXYLNORSTATINE

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Cyclohexylnorstatine [(2R, 3S)-3-amino-4-cyclohexyl-2-hydroxybutyric acid] (1) and allocyclohexylnorstatine [(2S, 3S)-3-amino-4-cyclohexyl-2-hydroxybutyric acid] (2), designed as key amino acids in renin inhibitors, were synthesized diastereoselectively and simply from Boc-L-phenylalaninol.
社団法人日本薬学会の論文
1989-09-25

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A SIMPLE DIASTEREOSELECTIVE SYNTHESIS OF CYCLOHEXYLNORSTATINE AND ALLOCYCLOHEXYLNORSTATINE
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A SIMPLE DIASTEREOSELECTIVE SYNTHESIS OF CYCLOHEXYLNORSTATINE AND ALLOCYCLOHEXYLNORSTATINE

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