1-Substituted Imidazoles as Useful Catalysts for Acylation of Alcohols
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概要
- 論文の詳細を見る
Acylation of alcohols with acid anhydrides or acid halides could be considerably accelerated by adding 1-substituted imidazoles as catalysts. The acylation with acid halides required the addition of triethylamine to capture the resulting acid. 1-Isopropyl-5-methylimidazole and 1-(4-methoxybenzyl)-5-methylimidazole showed higher catalytic activities than 4-dimethylaminopyridine (DMAP) for acylation of primary and secondary alcohols.
- 公益社団法人日本薬学会の論文
- 1983-10-25
著者
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原田 弘
Central Research Laboratories, Kissei Pharmaceutical Co., Ltd.,
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飯塚 欣二
Central Research Laboratories, Kissei Pharmaceutical Co., Ltd.,
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上條 哲聖
Central Research Laboratories, Kissei Pharmaceutical Co., Ltd.,
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山本 亮治
Central Research Laboratories, Kissei Pharmaceutical Co., Ltd.,
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上條 哲聖
キッセイ薬品工業株式会社中央研究所
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上条 哲聖
キッセイ薬品工業中央研究所
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山本 亮治
Central Research Laboratories Kissei Pharmaceutical Co. Ltd.
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飯塚 欣二
Central Research Laboratories Kissei Pharmaceutical Co. Ltd.
-
原田 弘
Central Research Laboratories Kissei Pharmaceutical Co. Ltd.
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